Recently, neutrophil/lymphocyte ratio (NLR) has been proved to be a useful indicator of inflammation and cardiovascular risk. Brachial-ankle pulse wave velocity is an indicator for early atherosclerotic changes. It is unknown whether NLR differs in subtypes of hypertension, and little research has been performed on the relationship between NLR and arteriosclerosis in subtypes of hypertension. The purpose of this article was to investigate their relationship. A total of 217 consecutive patients with hypertension and 132 persons without hypertension were included. All hypertension patients were divided into three groups according to office blood pressure. Brachial-ankle pulse wave velocity was elevated in patients with isolated systolic hypertension, isolated diastolic hypertension, and systolic and diastolic hypertension compared with normotensive controls. NLR in patients with isolated systolic hypertension and systolic and diastolic hypertension were higher than in normotensive controls. Correlation analysis revealed a positive correlation between NLR and brachial-ankle pulse wave velocity. Multivariate linear regression analysis showed that NLR was an effective indicator for brachial-ankle pulse wave velocity.
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http://dx.doi.org/10.1111/jch.13002 | DOI Listing |
Med Clin (Barc)
January 2025
Unidad de Investigación en Atención Primaria de Salamanca (APISAL), Gerencia de Atención Primaria de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, España; Red de Investigación en Cronicidad, Atención Primaria y Promoción de la Salud (RICAPPS) Salamanca, España; Departamento de Medicina, Universidad de Salamanca, Salamanca, España.
Introduction And Objectives: To analyse the increase of arterial stiffness over a five-year period and its relationship with cardiovascular risk factors and sex-based differences in a Spanish population without cardiovascular disease.
Methods: Longitudinal study. Analysis of the increase in arterial stiffness measures evaluated with SphygmoCor and Vasera of 480 subjects followed for 5 years of the 501 subjects included in the baseline evaluation, selected through random sampling stratified by age and sex, mean age of 55.
Nutrients
December 2024
Department of Health, Nutrition, and Food Sciences, Florida State University, 120 Convocation Way, Tallahassee, FL 32306, USA.
A pilot study was conducted to investigate the effect of four weeks of creatine monohydrate (CrM) on vascular endothelial function in older adults. In a double-blind, randomized crossover trial, twelve sedentary, healthy older adults were allocated to either the CrM or placebo (PL) group for four weeks, at a dose of 4 × 5 g/day for 5 days, followed by 1 × 5 g/day for 23 days. Macrovascular function (flow-mediated dilation [FMD%], normalized FMD%, brachial-ankle pulse wave velocity [baPWV], pulse wave analysis [PWA]), microvascular function (microvascular reperfusion rate [% StO/sec]), and biomarkers of vascular function (tetrahydrobiopterin [BH], malondialdehyde [MDA], oxidized low-density lipoprotein [oxLDL], glucose, lipids) were assessed pre- and post-supplementation with a four-week washout period.
View Article and Find Full Text PDFNutrients
December 2024
Research Network on Chronicity, Primary Care and Health Promotion (RICAPPS), 37005 Salamanca, Spain.
Background: Recent research highlights the potential role of sex-specific variations in cardiovascular disease. The gut microbiome has been shown to differ between the sexes in patients with cardiovascular risk factors.
Objectives: The main objective of this study is to analyze the differences between women and men in the relationship between gut microbiota and measures of arterial stiffness.
J Imaging Inform Med
January 2025
Department of Convergence Medicine, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-Ro 43-Gil, Seoul, 05505, Republic of Korea.
Although the relationships between basic clinical parameters and white matter hyperintensity (WMH) have been studied, the associations between vascular factors and WMH volume in general populations remain unclear. We investigated the associations between clinical parameters including comprehensive vascular factors and WMH in two large general populations. This retrospective, cross-sectional study involved two populations: individuals who underwent general health examinations at the Asan Medical Center (AMC) and participants from a regional cohort, the Korean Genome and Epidemiology Study (KoGES).
View Article and Find Full Text PDFPLoS One
January 2025
Graduate School of Education & Human Development, Nagoya University, Nagoya, Aichi, Japan.
The present study examined factors associated with trunk skeletal muscle thickness (MT, an index for the amount of skeletal muscle) and echo intensity (EI, an index for the content of non-contractile tissue, such as intramuscular adipose tissue) in young Japanese men and women in consideration of habitual dietary intake. Healthy men (n = 26) and women (n = 24) aged 20 to 26 were enrolled. Trunk MT and EI were evaluated using ultrasound imaging at the height of the 3rd lumbar vertebra.
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