Background: Pestiviruses in general, and Bovine Viral Diarrhea (BVD) in particular, present several potential targets for directed antiviral therapy.
Material And Methods: The antiviral effect of (Bge.) Kitag (Dog strangling vine: DS) extract on the bovine viral diarrhea (BVD) virus was tested. First, a cytotoxicity test in MDBK (Madin-Darby bovine kidney) cells was done with all organic extract concentrations.
Results: The cytotoxic concentration CC for the ethyl acetate (EA) extracts was 18.2 ug/ml. In the tissue culture, infectious dose (TCID) assay, the BVD virus decreased when treated with 18.2 ug/ml of the ethyl acetate extracts.
Conclusion: Ethyl acetate extracts and fractions of the DS extract could be used as a potential antiviral for BVD.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412225 | PMC |
| http://dx.doi.org/10.21010/ajtcam.v14i3.21 | DOI Listing |
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