AI Article Synopsis
- The notochord is an important embryonic structure in vertebrate development, with its remnants found in the nucleus pulposus of adult intervertebral discs.
- Pathological remnants can lead to chordomas, which are slow-growing tumors derived from the notochord.
- Clinicians involved in imaging or treating notochord-related conditions need to understand its anatomy, embryology, and associated pathologies.
Article Abstract
The notochord is a rod-like embryological structure, which plays a vital role in the development of the vertebrate. Though embryological, remnants of this structure have been observed in the nucleus pulposus of the intervertebral discs of normal adults. Pathologically, these remnants can give rise to slow-growing and recurrent notochord-derived tumors called chordomas. Using standard search engines, the literature was reviewed regarding the anatomy, embryology, molecular development, and pathology of the human notochord. Clinicians who interpret imaging or treat patients with pathologies linked to the notochord should have a good working knowledge of its development and pathology.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418029 | PMC |
| http://dx.doi.org/10.7759/cureus.1137 | DOI Listing |
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