Context: The salivary glands are the site of origin of a wide variety of neoplasms and are also relatively uncommon. The histopathology of these tumors is said to be the most complex and diverse of any organ in the body. The incidence of salivary gland tumors (SGTs) is claimed to be influenced by geographical and racial factors. Histopathological diagnosis plays a major role in the diagnosis of these neoplasms, with very few contribution using special stains, immunohistochemistry and cytogenetic studies.
Aims: Aimed at understanding the epidemiological pattern of these tumors and to compare our findings with reports done elsewhere.
Settings And Design: This is a retrospective study done at Pathology Department a Postgraduate Teaching Hospital, Tertiary Care Centre in Bagalkot, Karnataka, India. All the cases of SGTs, which had been recorded in a 3-year period from 2009 to 2012, were enrolled in the study.
Subjects And Methods: Clinical data were recorded and analyzed with respect to gender, age, site and histopathologic type.
Results: Data of 59 cases of SGTs were recorded, of which 43 (69.16%) cases were classified as benign tumors and 16 (22.39%) cases as malignant tumors. Male to female ratio (M/F) and the mean age of patients were 1:1.8 and 43 years, respectively. Pleomorphic adenoma (60.71%) and adenoid cystic carcinoma (14.94%) were the most common benign and malignant neoplasms.
Conclusions: Although the SGTs encountered were similar in most of their characteristics to those reported in India and other countries, some differences such as relative frequency, age and gender prevalence were discovered.
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http://dx.doi.org/10.4103/0973-029X.203762 | DOI Listing |
Clin Oral Investig
January 2025
State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Head and Neck Oncology, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.
Objectives: This study investigates the clinical and patient-reported outcomes of full-endoscopic parotidectomy compared to the conventional approach.
Methods: Between July 2021 and December 2023, patients who underwent parotidectomy were prospectively enrolled and assigned to either the full-endoscopic parotidectomy group (Group I) or the conventional surgery group (Group II). Clinical outcomes were evaluated, and patient-reported outcomes were assessed using a Visual Analogue Scale and five FACE-Q scales.
Ophthalmic Plast Reconstr Surg
January 2025
Adnexal Service, Moorfields Eye Hospital, London EC1V 2PD, United Kingdom.
Oncocytic carcinoma is a rare malignant neoplasm of oncocytic cells, such cells being characterized by abundant granular eosinophilic cytoplasm, invasive growth, and pronounced cellular pleomorphism. It may arise de novo, or through malignant transformation of a pre-existing benign oncocytoma. Oncocytic carcinoma most commonly occurs in the salivary glands, with rare involvement of the ocular adnexa where it mainly affects caruncle, conjunctiva, and lacrimal sac, and only very arises in the lacrimal gland.
View Article and Find Full Text PDFJ Clin Rheumatol
January 2025
Department of Radiology, Sannoh Hospital, Chiba-shi, Japan.
Objective: For early diagnosis and inquiry into the pathophysiology of Sjögren disease (SjD), salivary secretion and component levels, and salivary glands' uptakes in sialoscintigraphy were examined, in this cross-sectional study.
Methods: Patients who visited our hospital with suspected SjD between April 2016 and March 2020 were checked for unstimulated salivary secretion and β2-microglobulin, Na+, and cortisol levels in saliva. The patients who showed any abnormal salivary test results underwent sialoscintigraphy; the uptakes in the parotid, submandibular, and thyroid glands were compared using paired t test.
Cureus
December 2024
Oncology: Radiation Oncology, Tawam Hospital, Al Ain, ARE.
Background Adenoid cystic carcinoma (ACC) is a rare malignancy characterized by slow progression, local recurrence, and distant metastases. This study aims to evaluate the demographic patterns, clinical presentations, outcomes, and survival trends of patients with ACC. Methods A retrospective analysis of 14 patients diagnosed with ACC from 2010 to 2024 at a tertiary cancer center in the United Arab Emirates was conducted.
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