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Colitis Cystica Profunda: A Rare Cause of Rectal Bleeding.
Am J Gastroenterol
January 2025
Division of Gastroenterology & Hepatology, Department of Medicine, Barnes-Jewish Hospital/Washington University in St. Louis, St. Louis, Missouri, USA.
Acute Gastric Necrosis Secondary to Mesenteric Ischemia: A Case Report and Literature Review.
Cureus
December 2024
General Surgery, Hospital Regional de Alta Especialidad Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado B Veracruz, Veracruz, MEX.
Acute gastric dilation and necrosis, although rare, are most commonly associated with eating disorders. We present a case of a patient with a history of prior fundoplication and complete intestinal obstruction, which led to severe gastric dilation and subsequent gastric necrosis. The condition was successfully managed through partial gastrectomy.
View Article and Find Full Text PDFCell of origin and expression profiles of pseudomyxoma peritonei derived from the appendix.
Pathol Res Pract
December 2024
Division of Clinical Genome Research, Institute of Medical Science, The University of Tokyo, Tokyo, Japan. Electronic address:
Article Synopsis
- Pseudomyxoma peritonei (PMP) is a rare condition linked to mucin-producing tumors, usually starting in the appendix, leading to mucin buildup in the abdomen.
- Researchers conducted RNA-seq analysis on ten PMP cases and their healthy tissue to reveal 32 differently expressed genes, indicating that PMP tumors arise from goblet cells.
- The study found significant associations between PMP tumors and important biological processes like epithelial-mesenchymal transition, angiogenesis, and inflammation, with further analysis highlighting distinct gene expressions in different PMP types, suggesting more aggressive traits in peritoneal mucinous adenocarcinomas (PMCA).
Incidence, Clinicopathological Features, and Outcomes of Signet Ring Colorectal Carcinoma: A Retrospective Study.
Cureus
December 2024
Department of Surgical Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, PAK.
Background Signet ring cell carcinoma (SRCC) is a rare subtype of colorectal cancer with significant variations in clinical characteristics and poor prognosis. However, there is limited data available in Pakistan. Therefore, we analyzed to examine the incidence, clinicopathological features, treatments, and outcomes of SRCC in colorectal cancer cases in Pakistan.
View Article and Find Full Text PDFTwo Cases of Colonic Perforation Following Upper Gastrointestinal Barium Examinations.
Cureus
December 2024
Department of Surgery, Kitakyushu City Yahata Hospital, Kitakyushu, JPN.
This report presents two cases of colonic perforation that occurred following an upper gastrointestinal series (UGIS) with barium as part of a health screening. UGIS is a widely performed examination in Japan and is useful for the early detection of gastric cancer and peptic ulcers, but it carries a rare risk of causing serious gastrointestinal perforation. This study details the mechanisms of perforation, risk factors, difficulties in imaging diagnosis, and treatment options.
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