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| http://dx.doi.org/10.3389/fpsyg.2017.00601 | DOI Listing |
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Revisiting the concept of giant viruses.
Microbes Infect
December 2024
Laboratório de Vírus, Departamento de Microbiologia, Universidade Federal de Minas Gerais (UFMG). Belo Horizonte, Minas Gerais, 31270-901, Brazil. Electronic address:
Giant viruses have fascinated the scientific community due to their immense particles and extensive genomes. A significant surge of interest in the field has been observed over the past 20 years following the discovery of mimiviruses, the first amoeba-infecting viruses described. However, with the discovery of new amoeba viruses and those from other protists, the concept of "giant viruses" has become increasingly controversial in the scientific literature.
View Article and Find Full Text PDFInfectious Agents and Cancer journal has recently launched a new collection of papers about "Point-of-Care (POC) for HPV-related genital cancers" putting together some interesting works on the accuracy of HPV tests for screening. This editorial initiative gave us the opportunity to reflect on the relations between accuracy measures, prevalence and characteristics of the tested population in the case of HPV-based screening. In screening test evaluation, we look at the clinical accuracy of the test as an intrinsic characteristic of the assay, which interacts with the characteristics of the population, the result being the screening performance.
View Article and Find Full Text PDFReallocating Time Between 24-h Movement Behaviors for Obesity Management Across the Lifespan: A Pooled Data Meta-Analysis of More Than 9800 Participants from Seven Countries.
Sports Med
December 2024
Australian Catholic University, North Sydney, NSW, Australia.
Article Synopsis
- The study investigates how reallocating time among physical activity, sedentary behavior, and sleep affects obesity indicators like BMI and waist circumference across various age groups.
- Researchers analyzed data from 9,818 participants using isotemporal substitution models to understand the implications of these behavior changes.
- Results indicated that even small shifts of 10-30 minutes can significantly impact obesity, with reallocating moderate-to-vigorous physical activity (MVPA) to lighter activities or sedentary behavior having particularly detrimental effects.
A systematic narrative review of the involvement of executive functions in flying performance of pilots.
Front Neuroergon
December 2024
Fédération ENAC ISAE-SUPAERO ONERA, Université de Toulouse, Toulouse, France.
Piloting is a complex task that demands robust cognitive functions to handle multiple tasks simultaneously in a constantly changing environment. As a result, cognitive abilities, particularly executive functions (EFs), have gained significant importance in relation to flight performance. However, the specific EFs most critical for predicting flight performance remain unclear.
View Article and Find Full Text PDFAnti-amyloid treatments in Alzheimer's disease: elegance, evidence and ethics.
Adv Clin Exp Med
December 2024
NeuroActiva, Inc., San Jose, USA.
The so-called "amyloid cascade hypothesis" provides an elegant explanation of Alzheimer's disease (AD), has motivated the amyloid-lowering therapeutic strategy, and led to the elaboration of a rich experimental and conceptual toolkit for the field to progress. But it might be incorrect. The scientific evidence base supporting the efficacy and safety of current anti-amyloid antibody treatments in AD is weak.
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