AI Article Synopsis
- Cigarette smoking poses a significant global health challenge, and its effects on blood cells (erythrocytes) remain complex and not fully understood.
- This study examined the effects of smoking different amounts of cigarettes per day (10, 15, and 20) on the membranes of erythrocytes using advanced analysis techniques.
- Findings revealed that smoking alters membrane structure and properties, affecting how erythrocytes function, which may help explain some health issues linked to cigarette smoking.
Article Abstract
Cigarette smoking is a serious health problem throughout the world, with a complicated and not totally clear bio-effect. In this study, erythrocytes were obtained from healthy male volunteers aged 22 ± 2 years and, the possible effects of three cigarette smoking rates namely 10, 15 and 20 cigarette/day on erythrocytes membrane characteristics were examined by Fourier transform infrared spectroscopy (FTIR). The results of this study indicate many smoking-dependent variations on erythrocytes membrane without an obvious dose-response relationship. There was disruption in the acyl chain packing; changes in membrane order and phases as well as membrane proteins becoming more folded. These physico-chemical changes should have an impact on the function of erythrocytes and may explain the complex interaction of cigarette smoke mainstream with erythrocyte membrane and to some extent clarify the pathological processes associated with cigarette smoking.
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| http://dx.doi.org/10.4149/gpb_2016047 | DOI Listing |
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