The three-dimensional measurement technique using binary pattern projection with projector defocusing has become increasingly important due to its high speed and high accuracy. To obtain even faster speed without sacrificing accuracy, a ternary Gray code-based phase-unwrapping method is proposed by using even fewer binary patterns, which makes it possible to efficiently and accurately unwrap the phase. Theoretical analysis, simulations, and experiments are presented to validate the proposed method's efficiency and robustness.
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http://dx.doi.org/10.1364/AO.56.003660 | DOI Listing |
Comput Biol Med
December 2024
Department of Computer Science and Engineering, Visvesvaraya National Institute of Technology, South Ambazari road, Nagpur, 440022, Maharashtra, India.
In today's era, precise and timely diagnosis of ocular diseases are crucial as these disorders jeopardize millions of visions. Early detection and proactive management can minimize vision threatening complications from these disorders. High Myopia(HM) and Pathological Myopia(PM), are the globally prevalent ocular diseases, which can impair vision acuity and productivity across all age groups.
View Article and Find Full Text PDFbioRxiv
October 2024
Department of Chemical and Systems Biology, ChEM-H, and Stanford Cancer Institute, Stanford School of Medicine, Stanford University, Stanford, CA, USA.
is the most commonly mutated gene in cancer, but it remains recalcitrant to clinically meaningful therapeutic reactivation. We present here the discovery and characterization of a small molecule chemical inducer of proximity that activates mutant p53. We named this compound TRanscriptional Activator of p53 () due to its ability to engage mutant p53 and BRD4 in a ternary complex, which potently activates mutant p53 and triggers robust p53 target gene transcription.
View Article and Find Full Text PDFPrim Care Diabetes
December 2024
North Cumbria Integrated Care NHS FT, Carlisle CA2 7HY, UK; University of Cumbria, Carlisle CA1 2HH, UK. Electronic address:
Aims: Diabetic patients are at elevated risk of neuropathy; early detection is desirable to minimise the risk of complications. The Medipin pin-prick device was appraised as a screening tool for diabetic neuropathy.
Methods: Prospective cross-sectional comparative screening study in primary care setting, involving 389 participants with type 2 diabetes mellitus.
Eur J Med Chem
December 2024
Department of Chemical and Systems Biology, ChEM-H and Stanford Cancer Institute, Stanford School of Medicine, Stanford University, Stanford, CA, USA. Electronic address:
Chemically induced proximity modalities such as targeted protein degradation (TPD) hold promise for expanding the number of proteins that can be manipulated pharmacologically. However, current TPD strategies are often limited to proteins with preexisting ligands. Molecular glues (e.
View Article and Find Full Text PDFSci Rep
September 2024
Department of Mechanical, Bioresources and Biomedical Engineering, Science Campus, University of South Africa, Private Bag X6, Florida, 1709, South Africa.
The worldwide exploration of the ethanolysis protocol (EP) has decreased despite the multifaceted benefits of ethanol, such as lower toxicity, higher oxygen content, higher renewability, and fewer emission tail compared to methanol, and the enhanced fuel properties with improved engine characteristics of multiple-oily feedstocks (MOFs) compared to single-oily feedstocks. The study first proposed a strategy for the optimisation of ethylic biodiesel synthesis from MOFs: neem, animal fat, and jatropha oil (NFJO) on a batch reactor. The project's goals were to ensure environmental benignity and encourage the use of totally biobased products.
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