Dental implants have become a suitable treatment option for patients experiencing tooth loss and a popular choice among clinicians for immediate tooth replacement. Because of modifications in implant designs and development in immediate restoration and loading protocols, dental implant treatment can be reduced to a single procedure instead of multiple processes, hence providing the patient with a streamlined treatment that is typically much less invasive with immediate-tooth replacement. The purpose of this paper is to review the immediate restoration of dental implant(s) procedure and validate its position in treatment protocols by presenting success rates documented for more than 15 years and with 5000 implants. Also, recommendations for the management of different alveolar contours and defects will be presented, which have been encountered by the author when performing the immediate restoration procedure throughout this 15-year period.
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Background: Genetic studies have established that loss of function SORL1 gene variants are associated with Alzheimer's disease (AD). SORL1 encodes an endosomal trafficking receptor, SORLA, which regulates endosomal protein recycling through its interaction with the retromer core complex (consisting of VPS26, VPS35 and VPS29). Deficits in the levels and function of the SORLA-retromer complex are thought to underlie AD.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Alzheimer's Disease Research Center, New York University Langone Health, New York, NY, USA.
Background: Behavioral and psychological symptoms of dementia (BPSD) occur frequently in persons with Alzheimer's disease (PAD). They cause suffering, institutionalization, carepartner distress, depression, burden, and decreased PAD-carepartner quality of life. Brexpiprazole approval advanced the AD treatment armamentarium.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Clinic of Cardiovascular Diseases named after Most Holy John Tobolsky, Moscow, Moscow, Russia.
Background: Most cerebrovascular lesions are aggravated by dementia. This study examines the possibility of reducing dementia by stimulating cerebral angiogenesis and neurogenesis using Transcatheter Intracerebral Laser Photobiomodulation Therapy (PBMT) in patients with Alzheimer's disease (AD), distal cerebral atherosclerosis, Binswanger's disease (BD), and vascular parkinsonism (VP).
Methods: The study included 404 patients with dementia, aged 29-81 (mean age 78).
J Hand Surg Eur Vol
January 2025
Center for Orthopedic Trans-Disciplinary Applied Research, Tehran University of Medical Sciences, Tehran, Iran.
We retrospectively reviewed the outcome of triple nerve transfer, including reinnervation of brachioradialis and double nerve transfer surgery in C5-C6 traumatic brachial plexus injuries. IV.
View Article and Find Full Text PDFActa Chir Orthop Traumatol Cech
January 2025
University of Mersin, School of Medicine, Department of Orthopaedics and Traumatology, Division of Hand Surgery, Mersin, Turkey.
Purpose Of The Study: The aim of this study to evaluate the subjective and objective results of Extensor indicis proprius (EIP) to extensor pollicis longus (EPL) transfer with an emphasis on donor site morbidity.
Material And Methods: 17 patients (59% men, 41% women) who underwent EIP-EPL transfer were retrospectively analyzed. The mean age was 43 (9-64) years, and the mean follow-up was 72 (19-124) months.
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