Zirconocene catalyzed diastereoselective carbometalation of cyclobutenes.

Chem Sci

The Mallat Family Laboratory of Organic Chemistry , Schulich Faculty of Chemistry and Lise Meitner-Minerva Center for Computational Quantum Chemistry , Technion-Israel Institute of Technology, Technion City , Haifa 32000 , Israel . Email: ; ; Tel: +972-4-829-37-09.

Published: January 2017

The regio- and diastereoselective zirconocene-catalyzed carbomagnesiation of cyclobutenes is herein reported to afford configurationally stable cyclobutylmagnesium species that could subsequently react with a large variety of electrophiles to give polysubstituted cyclobutane species as a single diastereoisomer.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365058PMC
http://dx.doi.org/10.1039/c6sc02617fDOI Listing

Publication Analysis

Top Keywords

zirconocene catalyzed
4
catalyzed diastereoselective
4
diastereoselective carbometalation
4
carbometalation cyclobutenes
4
cyclobutenes regio-
4
regio- diastereoselective
4
diastereoselective zirconocene-catalyzed
4
zirconocene-catalyzed carbomagnesiation
4
carbomagnesiation cyclobutenes
4
cyclobutenes reported
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!