AI Article Synopsis
- - Vascular twin nevi (VTN) involve the coexistence of a telangiectatic naevus and a nevus anemicus in the same area of skin.
- - Nevus anemicus is a type of vascular anomaly that appears as light-colored patches on the skin while maintaining normal levels of melanin and melanocytes.
- - The case presented illustrates a rare example of the twin spotting phenomenon, where genetic crossing-over during cell division leads to the development of two distinct vascular anomalies in close proximity.
Article Abstract
Vascular twin nevi (VTN) are characterized by the simultaneous dermatological manifestatiton of a telangiectatic naevus close to a nevus anemicus. Nevus anemicus (NA) is a vascular anomaly characterized by localized pale patches with normal melanine and melanocyte level. According to twin spotting phenomenon crossing-over in heterozygous somatic-cells during mitosis results in two different offspring homozygous cells. Consequent to this mechanism, two different vascular anomalies may occur at the same region. We present a patient with VTN and NA combination which we think serves as an example for a rare twin spotting phenomenon in the literature.
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| http://dx.doi.org/10.1002/ajmg.a.38117 | DOI Listing |
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