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Positive real-time PCR in pneumococcal meningitis 12 hours after initiation of antibiotic therapy - case report.
BMC Neurol
January 2025
Department of Neurology, LMU University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany.
Background: Purulent meningitis poses a significant clinical challenge with high mortality. We present the case of a 54-year-old female transferred to our emergency department with suspected bacterial meningitis, later diagnosed as an Austrian syndrome.
Case Presentation: The patient exhibited subacute somnolence, severe headache, nausea and fever.
Case report: Trauma-induced invasive syndrome presenting with liver abscess, lung abscess, endophthalmitis, and purulent meningitis.
Front Med (Lausanne)
January 2025
Department of Neurology, Guangxi University of Science and Technology First Affiliated Hospital, Liuzhou, China.
Purpose: This study aims to explore the underlying causes, diagnostic strategies, and treatment approaches of trauma-induced invasive syndrome (KPIS) through a rare case report. By highlighting the role of trauma as a potential trigger for KPIS, particularly in high-risk populations such as individuals with diabetes, this study seeks to provide valuable insights for improving clinical outcomes and promoting public health awareness.
Background: invasive syndrome is a multi-organ infectious disease commonly associated with complications such as liver abscess, lung abscess, endophthalmitis, and purulent meningitis, with high mortality and disability rates.
Four-month-old infant with chronic granulomatous disease and invasive aspergillosis with bone involvement.
Biomedica
December 2024
Laboratorio de Inmunodeficiencias, Instituto Nacional de Pediatría, Ciudad de México, México.
Chronic granulomatous disease is the inborn error of immunity with the highest frequency of invasive aspergillosis. In this context, invasive aspergillosis is frequent in adolescence, with rare cases before one year of age. We present a case of chronic granulomatous disease and invasive aspergillosis in a four-month-old infant.
View Article and Find Full Text PDFBackground: Group B streptococcus (GBS) causes neonatal invasive disease, mainly sepsis and meningitis. Understanding the clinical characteristics, laboratory tests, and antibiotic resistance patterns of GBS invasive infections provides reliable epidemiological data for preventing and treating GBS infections.
Methods: Clinical characteristics and laboratory test results from 86 patients with neonatal invasive disease (45 cases of early-onset disease [EOD] and 41 cases of late-onset disease [LOD]) recruited from Fujian Maternity and Child Health Hospital between January 2012 and December 2021 were analyzed.
Intrapleural fibrinolytic therapy for pleural infections: Outcomes from a cohort study.
Ann Acad Med Singap
December 2024
Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore.
Introduction: Pleural infections are a significant cause of mortality. Intrapleural fibrinolytic therapy (IPFT) utilising alteplase and dornase is a treatment option for patients unsuitable for surgery. The optimal dose of alteplase is unknown, and factors affecting treatment success in an Asian population are unclear.
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