Objectives: To assess Jordanian hypertensive patients' adherence rate to hypertension therapeutic regimen (HTR) and to identify the strongest predictors of adherence rate among such patients.
Design And Sample: A descriptive comparison design and convenience sampling were used. The sample comprised 192 participants who came to their regular appointments in a public healthcare center.
Measurement: The Hill-Bone Compliance to High Blood Pressure Therapy Scale and the Hypertension Knowledge-Level Scale were used to assess adherence to HTR and knowledge of hypertension, respectively.
Results: The mean total score for adherence to HTR was 87.3, and 82.8% of participants reported good adherence overall. Adherence scores were significantly higher among women, less educated, unemployed participants, those with comorbidities, those with a negative family history of hypertension, and those who visited their physicians regularly. To identify the most significant predictors of adherence to HTR, multiple linear regression analysis was performed. Results indicated that good adherence to HTR was predicted by greater knowledge about hypertension and regularly visiting a physician.
Conclusions: Adherence to taking antihypertensive medications was good overall among the study participants; these participants, however, were less interested in adherence to reduced sodium intake and keeping up with medical appointments. Hypertensive patients appear to follow instructions related to pharmacological management and are less likely to comply with other elements of HTR.
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http://dx.doi.org/10.1080/10641963.2016.1247164 | DOI Listing |
Sci Rep
December 2023
Department of Medical and Molecular Genetics, Indiana University School of Medicine, Raclin-Carmichael Hall, 1234 Notre Dame Ave., South Bend, IN, 46617, USA.
Medicina (B Aires)
November 2023
División Tisioneumonología, Hospital Dr. F. J. Muñiz, Buenos Aires, Argentina.
Mixed infection by Mycobacterium tuberculosis (Mtb) consists in the simultaneous coexistence in the same patient of two different strains of Mtb or 2 different variants of the same strain. When one of the variants selects for resistance mutations, it is called monoclonal heteroresistance (HTR); if there are 2 different strains, one sensitive and one resistant (or with different resistance patterns), it is called polyclonal HTR. Three cases of HIV/AIDS patients are presented, all with repeated treatment adherence problems, in whom monoclonal HTR was diagnosed through Mtb complete genomic sequentiation with the coexistence of two variants of the same strain isolated from samples from lung and lymph nodes, with different resistance profiles in each case.
View Article and Find Full Text PDFMutagenesis
February 2023
Faculty of Pharmacy, Department of Pathobiology, University of Belgrade, Belgrade, Serbia.
An increase of reactive oxygen species in the placenta and oxidative disbalance has been recognized as a significant factor contributing to pregnancy complications. Dietary intake of food rich in antioxidants during pregnancy could exert a protective role in the prevention of adverse outcomes such as preeclampsia, miscarriage, and others. Flavonoid taxifolin has shown numerous health-promoting effects in a large number of studies conducted on animals, as well as various human cell types in vitro.
View Article and Find Full Text PDFFront Cell Infect Microbiol
July 2022
Poursina Hakim Digestive Diseases Research center, Isfahan University of Medical Sciences, Isfahan, Iran.
There is increasing evidence showing that microbial dysbiosis impacts the health and cancer risk of the host. An association between adherent-invasive (AIEC) and colorectal cancer (CRC) has been revealed. Cyclomodulins (CMs) have been receiving increasing attention for carcinogenic changes.
View Article and Find Full Text PDFIran J Basic Med Sci
November 2020
Department of Haematology and Blood Transfusion, College of Medicine, University of Lagos, Idi-Araba, Lagos, Nigeria.
Objectives: Efavirenz, has proven to be effective in suppressing human immunodeficiency virus (HIV) viral load; however, complaints of sleep disorders including hallucination, and insomnia have greatly contributed to non-adherence to antiretroviral therapy. This study aimed at investigating therapeutic activities of naringenin on efavirenz-induced sleep disorder.
Materials And Methods: Sixty mice were divided into six groups of control, combination antiretroviral therapy (cART), efavirenz, naringenin, naringenin/efavirenz and naringenin/cART.
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