AI Article Synopsis
- Several studies have found methylphenidate (MPH) in waterways, but its effects on aquatic life are not fully understood.
- Research on zebrafish revealed that MPH reduces cortisol responses to stress while simultaneously causing stress in the fish.
- The presence of MPH in aquatic environments may significantly change neuroendocrine and behavioral responses in fish, potentially affecting their survival and well-being.
Article Abstract
Several studies have reported the presence of methylphenidate (MPH) in effluents; however, its impacts on aquatic life are not yet well understood. Here, we investigated the effects of acute exposure on endocrine and behavioral stress responses to environmentally relevant concentrations of MPH in zebrafish. We show that MPH blunts the response of cortisol to stress in zebrafish. On the other hand, MPH stresses fish per se. Additionally, MPH seems to modulate anxiety-like behaviors. We conclude that the presence of MPH in aquatic environments can alter neuroendocrine and behavior responses, which might considerably impact fish survival and welfare.
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| http://dx.doi.org/10.1016/j.neulet.2017.04.039 | DOI Listing |
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