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A Multi-Skilled Mathematical Model of Bacterial Attachment in Initiation of Biofilms.
Microorganisms
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IRMAR, CNRS UMR 6625, Université de Rennes, F-35000 Rennes, France.
The initial step of biofilm formation is bacteria attachment to biotic or abiotic surfaces and other bacteria through intra or interspecies interactions. Adhesion can be influenced by physicochemical conditions of the environment, such as iron. There is no available mathematical model of bacterial attachment giving realistic initiation rather than random adhesion.
View Article and Find Full Text PDFDNA damage induced cellular senescence and it's PTEN-armed exosomes-the warriors against prostate carcinoma cells.
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Department of Life Science and Biotechnology, Jadavpur University, Kolkata, 700032, India.
Exosomes are one type of small extracellular vesicles (EVs) having a size range of 30-150 nm and secreted by the endosomal compartment of most eukaryotic cells. It has been found that exosomes (EVs) can serve as a communicating vehicle to transfer information among cells and thus can be associated with numerous physiological and pathological functions. In this study, we have isolated exosomes (EVs) from two different human cancer cell lines.
View Article and Find Full Text PDFElectrochemical and Spectroelectrochemical Studies on the Reactivity of Perimidine-Carbazole-Thiophene Monomers towards the Formation of Multidimensional Macromolecules versus Stable π-Dimeric States.
Materials (Basel)
April 2021
Faculty of Chemistry, Silesian University of Technology, M. Strzody 9, 44-100 Gliwice, Poland.
During research on cross-linked conducting polymers, double-functionalized monomers were synthesized. Two subunits potentially able to undergo oxidative coupling were used-perimidine and, respectively, carbazole, 3,6-di(hexylthiophene)carbazole or 3,6-di(decyloxythiophene)carbazole; alkyl and alkoxy chains as groups supporting molecular ordering and 14-benzo[4,5]isoquinone[2,1-a]perimidin-14-one segment promoting CH⋯O interactions and π-π stacking. Electrochemical, spectroelectrochemical, and density functional theory (DFT) studies have shown that potential-controlled oxidation enables polarization of a specific monomer subunit, thus allowing for simultaneous coupling via perimidine and/or carbazole, but mainly leading to dimer formation.
View Article and Find Full Text PDFCase 13-2017. A 41-Year-Old Man with Hearing Loss, Seizures, Weakness, and Cognitive Decline.
N Engl J Med
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From the Departments of Neurology (H.M.R.), Radiology (W.A.C.), Pediatrics (A.K.), and Pathology (D.H.O.), Massachusetts General Hospital, and the Departments of Neurology (H.M.R.), Radiology (W.A.C.), Pediatrics (A.K.), and Pathology (D.H.O.), Harvard Medical School - both in Boston.
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