Toxic Keratoconjunctivitis.

Eye Contact Lens

Department of Ophthalmology and Visual Sciences (G.L.P., A.J.L.), Washington University in St. Louis, St, Louis, MO; and Department of Ophthalmology and Visual Science (J.J.R., A.V.F.), University of Chicago, Chicago, IL.

Published: September 2018

AI Article Synopsis

  • Toxic keratoconjunctivitis (TK) is a serious but often overlooked complication resulting from the use of eye medications or exposure to certain environments.
  • Identifying the cause requires a thorough patient history and clinical examination, with common triggers being preservatives in eye drops, topical antibiotics, and anesthetics.
  • Effective management strategies include using preservative-free options and, in severe cases, may involve topical steroids, antibiotics, or even surgery to prevent lasting eye damage.

Article Abstract

Toxic keratoconjunctivitis (TK) is an underrecognized complication of ophthalmic drug use and various environmental or occupational exposures. A detailed history and clinical examination are important to identify the offending agent(s). Common drug-related causes of TK include preservatives in ophthalmic medications, topical antimicrobials, and topical anesthetics. Alternatives to benzalkonium chloride as well as preservative-free formulations should be considered in patients requiring long-term topical medication. More advanced cases of TK may require preservative-free topical steroids and/or antibiotics, and occasionally surgical intervention. Early recognition and appropriate management of TK may help prevent permanent ocular and visual damage.

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Source
http://dx.doi.org/10.1097/ICL.0000000000000392DOI Listing

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