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Background Transfusion-transmissible infections (TTIs) pose a significant risk to blood transfusion safety, especially in low-resource settings. TTIs include infections such as HIV, hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis, and malaria. Over four years, this study assesses the seroprevalence of TTIs among voluntary blood donors at a tertiary care center.

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Background: A transfusion-transmissible infection (TTI) refers to any infection that can be spread from one person to another through the injection of blood or blood products. The prevalence of these infections varies across countries, influenced by the disease burden within each population. To assess the severity of TTIs, the World Health Organization (WHO) has mandated pre-transfusion blood tests for Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), and syphilis.

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Serological markers of transfusion transmissible infections and ABO blood groups in Najran, Saudi Arabia.

Saudi Med J

July 2024

From the Department of Clinical Laboratory Sciences (Alshehri, Alshahrani MM, Asiri, Al Awad, Alhasaniah, Almazni, Alshamrani, Elnoubi), College of Applied Medical Sciences, Najran University; from the Health Research Center (Alshehri), Najran University; from the Department of Clinical Laboratory Sciences (Aboluluy), Najran University Hospital, Najran University, Najran; from the Department of Public Health (Alshahrani AJ), General Directorate of Health Affairs in Asir Region, Asir; from the Department of Clinical Laboratory Sciences (Saif, Hakami), College of Applied Medical Sciences, King Khalid University, Abha; from the Department of Pathology and Medical Laboratory - Molecular Genetics (Almohi), University Hospital, King Khalid University, Abha; from the Department of Clinical Laboratory Sciences (Othman), College of Applied Medical Sciences, Shaqra University, Shaqra, Kingdom of Saudi Arabia; from the Department of Medical Microbiology & Parasitology (Irekeola), School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia; from the Microbiology Unit, Department of Biological Sciences (Irekeola), College of Natural and Applied Sciences, Summit University Offa, Kwara, Nigeria; and from the Cardiovascular Signaling Division (Mohammed Abdul), Huntington Medical Research Institutes, California, United States of America.

Objectives: To ascertain the prevalence of transfusion transmissible infections (TTIs) across diverse donor groups in the Najran province. Additionally, to establish a potential association between the development of TTI and the donors' blood group, as determined by the ABO/Rh blood grouping system.

Methods: Blood donation data of 4120 donors, spanning from January to December 2020, were retrospectively reviewed.

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Seroprevalence of human immunodeficiency virus in African blood donors: a systematic review and meta-analysis.

EBioMedicine

July 2024

MEDCIDS, Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine of the University of Porto, Porto, Portugal; CINTESIS@RISE-Center for Health Technology and Services Research (CINTESIS) & Health Research Network Associated Laboratory (RISE) Faculty of Medicine, University of Porto, Porto, Portugal. Electronic address:

Background: In developing countries, the safety of blood transfusions remains an important public health concern as it is associated with a higher risk of transfusion-transmissible infections (TTIs). In this study, we aimed to estimate the seroprevalence of HIV among blood donors in Africa and assess the temporal trends and regional differences within the continent through a systematic review and meta-analysis.

Methods: Seven electronic databases (PubMed, Web of Science, Cochrane, Scopus, HINARI, Global Index Medicus and Clinical.

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Background And Objectives: Malaria was the first ever reported case of transfusion transmitted infection (TTI). Transfusion transmissible malaria (TTM) can result in febrile transfusion reaction in the recipient. TTM can be fatal if the blood transfusion recipient is from vulnerable population i.

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