In an effort to expand the availability of simple polysulfides for HS donation, we report here the synthesis and HS release profiles of bis(aryl) and bis(alkyl) tetrasulfides. The tetrasulfide donors release HS in a first-order dependence on reduced glutathione (GSH) and release more HS than the commonly used trisulfide DATS.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022400 | PMC |
| http://dx.doi.org/10.1021/acs.orglett.7b00858 | DOI Listing |
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