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Case report - Hyperthermia and nuclear hypersegmentation of blood cells.
Lab Med
January 2025
Laboratory Department, Montauban Hospital Center, Montauban, France.
This case report describes a patient with a medical history of schizophrenia, found in a coma with hyperthermia, likely due to classic heatstroke. The white blood cells observed on the blood smear showed cytological abnormalities characterized by multilobed nuclei, which could be early signs of cell death. The evolution into multiorgan failure led rapidly to death.
View Article and Find Full Text PDFOdontogenic neoplasms demonstrate unique histopathological features and are thought to arise from the germinal tissues of the developing tooth germ, effectively restricting their anatomic origin to the tooth-bearing regions of the jaw and directly associated soft tissues of the oral cavity. Ectopic odontogenic-like neoplasms located in the skin of cats, rabbits, and human beings challenge these assumptions. Here we describe the clinical, pathological, and immunohistochemical features of 6 spontaneously occurring odontogenic-like neoplasms arising in the cutaneous tissue of the cheek in client-owned pet rabbits, including ameloblastoma-like (n = 3), ameloblastic fibroma-like (n = 2), and ameloblastic carcinoma-like neoplasms (n = 1).
View Article and Find Full Text PDF[Embryonal botryoid rhabdomyosarcoma of the uterus].
Medicina (B Aires)
October 2022
Servicio de Patología, Hospital Interzonal General de Agudos Gral. San Martín, La Plata, Buenos Aires, Argentina.
Rhabdomyosarcoma is a malignant neoplasm of mesenchymal origin with skeletal striated muscular differentiation. It is the most common sarcoma of childhood and has four subtypes: embryonal, alveolar, pleomorphic and spindle cell/sclerosing. Of all of them, the embryonal one is the most prevalent and presents a variant, botryoid, which usually involves hollow organs in the form of a multilobed polypoid mass.
View Article and Find Full Text PDFBotryoid neutrophils in sepsis caused by influenzae virus A.
EJHaem
November 2020
Hematology Laboratory Institut Catala De La Salut Girona Spain.
A 13-year-old patient was admitted to our hospital with severe respiratory distress, fever, and signs of meningeal infection. A positive result of swine flu was obtained by RT-PCR. All bacterial cultures were negative.
View Article and Find Full Text PDFA novel Siglec-F neutrophil subset in the mouse nasal mucosa exhibits an activated phenotype and is increased in an allergic rhinitis model.
Biochem Biophys Res Commun
June 2020
Department of Fundamental Biosciences, Shiga University of Medical Science, Otsu, Shiga, 520-2192, Japan. Electronic address:
Neutrophils are important phagocytic cells for host defense against pathogens. They are rapidly recruited to the site of infection, release antimicrobial peptides and cytokines, and engulf and kill microbes. Neutrophils also accumulate in allergic inflammatory sites.
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