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Dengue haemorrhagic fever (DHF) in pregnancy.
BMJ Case Rep
March 2025
Obstetrics and Genecology, SDM College of Medical Sciences and Hospital, Dharwad, India.
Dengue haemorrhagic fever (DHF) is a common tropical disease. An increasing frequency of dengue fever and DHF in pregnancy is being observed, with a rising incidence among adults. This case report describes the management of a woman in her early 30s, gravida 3, para 2, at 34 weeks of gestation, presenting with DHF and dengue shock syndrome, with a history of two previous caesarean sections.
View Article and Find Full Text PDFControlling Aedes mosquitoes using densovirus-based biolarvicides: Current status and prospects.
J Invertebr Pathol
March 2025
Maladies Infectieuses et Vecteurs, Ecologie, Génétique, Evolution et Contrôle (MIVEGEC), Montpellier University, IRD, CNRS, Montpellier, France. Electronic address:
Aedes albopictus and Aedes aegypti are the main vectors of emerging arboviruses, such as dengue, chikungunya and Zika viruses. Entomopathogenic viruses, such as densoviruses, might represent more environmentally friendly control methods. Densoviruses are single-stranded DNA viruses belonging to the Parvoviridae family and three species are known to infect mosquitoes: Protoambidensovirus dipteran, Brevihamaparvovirus dipteran 1, and Brevihamaparvovirus dipteran 2.
View Article and Find Full Text PDFProtocol for Screening Host-Targeting Antivirals (HTAs) Using Human PBMCs and pDCs.
Bio Protoc
March 2025
Tropical Infectious Disease Research and Education Centre (TIDREC), Universiti Malaya, Kuala Lumpur, Malaysia.
This protocol offers an ex vivo method for screening host-targeting antivirals (HTAs) using human peripheral blood mononuclear cells (PBMCs) or plasmacytoid dendritic cells (pDCs). Unlike virus-targeting antivirals (VTAs), HTAs provide advantages in overcoming drug resistance and offering broad-spectrum protection, especially against rapidly mutating or newly emerging viruses. By focusing on PBMCs or pDCs, known for their high production of humoral factors such as Type I interferons (IFNs), the protocol enables the screening of antivirals that modulate immune responses against viruses.
View Article and Find Full Text PDFAge-specific kinetics of neutralizing antibodies and infection enhancement among ≤1 year-old Indian infants.
Front Cell Infect Microbiol
March 2025
Translational Virology, Interactive Research School for Health Affairs (IRSHA), Bharati Vidyapeeth (Deemed to be University), Pune, India.
Background: Infants born to dengue-immune mothers acquire maternal antibodies to dengue. Maternal antibodies decline over time, making infants susceptible to primary dengue infections. Another important concern is the role of maternal antibodies in causing antibody-dependent enhancement (ADE) during primary infections.
View Article and Find Full Text PDFBackground And Aims: A more accurate assessment of the disease's incidence and fatality rate over the previous years could help with future outbreak detection and containment. Therefore, this scoping review was conducted to compile the results of research on dengue investigation in Bangladesh in terms of knowledge, attitudes, and practices; risk factors; clinical presentations; and stereotypes of dengue.
Methods: The final analysis included 27 studies that satisfied the inclusion criteria.
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