AI Article Synopsis
- Male infertility is a significant issue for couples globally, but the reasons behind unexplained cases (idiopathic) are still not well understood.
- Recent research indicates that circulating cell-free nucleic acids might be involved in male infertility and could provide insights into its causes.
- The review highlights the potential of these nucleic acids as biomarkers for diagnosing male infertility in clinical settings, paving the way for better understanding and treatment options.
Article Abstract
Male infertility is a devastating problem that affects many couples worldwide. However, the molecular mechanisms and causes of idiopathic male infertility remain unclear. Circulating cell-free nucleic acids have an important role in human physiology and emerging evidence suggests that they play a role in male infertility. This review summarizes recent results on cell-free and intracellular nucleic acids in male infertility and discusses their potential use as biomarkers of male infertility in the clinical practice.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399401 | PMC |
| http://dx.doi.org/10.1186/s12610-017-0052-0 | DOI Listing |
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