Aim: Placement of implants in the maxillary anterior region needs to be preceded by careful analysis of the area as in addition to the functional aspect the esthetic outcome is of prime importance. This descriptive study evaluated anatomical characteristics and dimensions of the nasopalatine canal (NC) from coronal, sagittal and axial aspects using cone beam computed tomography (CBCT) giving it a three dimensional analytical approach. Also the dimensions of the corresponding buccal bone plate (BBP) of the alveolar process were evaluated. Additionally, the influence of age and gender on these characteristics was also analyzed.
Methods: A total of 81-CBCT scans of patients with one or no upper central incisors present were selected. Sagittal slices were used for measurements of the NC and BBP and to evaluate shape of the NC. Coronal slices were used to assess NC shape and axial slices to assess number of incisive foramina and foramina of Stenson.
Results: The most prevalent canal shape was: cylindrical (48.14 %) in sagittal aspect; Y-type (49.38 %) in coronal aspect; and one incisive foramen with two Stenson's foramina [1-(2-5)] (60.49 %) in axial aspect. Mean NC length was 11.13 ± 3.23 mm; statistically significant differences were detected between genders ( < 0.001). Mean nasopalatine angle was 69.32° ± 7.70. Mean BBP length was 17.12 ± 3.97 mm and mean BBP width was 5.71 ± 1.29 mm, significant differences were detected between genders ( < 0.001).
Conclusion: The current study demonstrates variability of the NC in terms of anatomical characteristics and dimensions; hence, a thorough CBCT analysis is highly recommended for better surgical outcomes and to reduce the post-operative complications in implant dentistry.
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http://dx.doi.org/10.1007/s12663-016-0879-5 | DOI Listing |
JACC Clin Electrophysiol
January 2025
Montreal Heart Institute, Montreal, Québec, Canada.
Background: Ventricular tachycardia (VT) substrate characteristics before transcatheter pulmonary valve replacement (TPVR) in repaired tetralogy of Fallot (rTOF) are unknown.
Objectives: In this study, the authors sought to evaluate substrates for sustained monomorphic VT before TPVR in rTOF.
Methods: Retrospective (2017 to 2021) and prospective (commencing 2021) rTOF patients with native right ventricular outflow tract referred for electrophysiology study (EPS) before TPVR were included.
Ann Thorac Surg
January 2025
Congenital Heart Center at Mott Children's Hospital, Ann Arbor, MI.
Background: The Pediatric Interagency Registry for Mechanical Circulatory Support (Pedimacs), supported by The Society of Thoracic Surgeons, provides detailed information on pediatric patients supported with ventricular assist devices (VADs).
Methods: From September 19, 2012, to December 31, 2023, there were 1648 devices in 1349 patients (<19 years) from 39 North American Hospitals with 100 patients enrolled in 2023.
Results: Cardiomyopathy was the most common underlying etiology (59%), followed by congenital heart disease (26%) and myocarditis (8%).
J Magn Reson
January 2025
UC Berkeley - UCSF Graduate Program in Bioengineering, 1700 4th St, San Francisco, CA 94158, USA; Radiology and Biomedical Imaging, University of California, San Francisco, 1700 4th St, San Francisco, CA 94158, USA.
Fitting rate constants to Hyperpolarized [1-C]Pyruvate (HP C13) MRI data is a promising approach for quantifying metabolism in vivo. Current methods typically fit each voxel of the dataset using a least-squares objective. With these methods, each voxel is considered independently, and the spatial relationships are not considered during fitting.
View Article and Find Full Text PDFWorld J Gastrointest Oncol
January 2025
Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest 050474, Romania.
Background: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive lethal malignancy with limited options for treatment and a 5-year survival rate of 11% in the United States. As for other types of tumors, such as colorectal cancer, aberrant lipid synthesis and reprogrammed lipid metabolism have been suggested to be associated with PDAC development and progression.
Aim: To identify the possible involvement of lipid metabolism in PDAC by analyzing in tumoral and non-tumoral tissues the expression level of the most relevant genes involved in the long-chain fatty acid (FA) import into cell.
Hum Brain Mapp
January 2025
Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, Mexico.
Premature infants, born before 37 weeks of gestation can have alterations in neurodevelopment and cognition, even when no anatomical lesions are evident. Resting-state functional neuroimaging of naturally sleeping babies has shown altered connectivity patterns, but there is limited evidence on the developmental trajectories of functional organization in preterm neonates. By using a large dataset from the developing Human Connectome Project, we explored the differences in graph theory properties between at-term (n = 332) and preterm (n = 115) neonates at term-equivalent age, considering the age subgroups proposed by the World Health Organization for premature birth.
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