Background: Results from 2 cohort studies in Scotland established in the 1940s and 1950s (Aberdeen and Motherwell) suggested that a high protein diet during pregnancy might adversely influence offspring blood pressure at adult age. Our objective was to examine this association in the Danish Fetal Origins Cohort (DaFO88).
Methods And Results: This was a prospective birth cohort of 965 women who gave birth in 1988-1989 in Aarhus, Denmark, and whose offspring (n=434) participated in a clinical examination ≈20 years later. Macronutrient intake was assessed in gestational week 30. Multivariable adjusted linear regression was used to examine the relation between higher maternal protein intake, at the expense of carbohydrates, and offspring blood pressure (isocaloric substitution). Main analyses were adjusted for mother's age during pregnancy, prepregnancy body mass index, parity, smoking during pregnancy, educational level, and offspring's sex. The mean total energy intake was 8.7 MJ/day (SD 2.3 MJ/day). The mean energy from carbohydrate, fat, and protein intake was 51, 31, and 16 of total energy, respectively. The results showed that after adjustment, higher maternal protein intake was associated with slightly higher offspring diastolic blood pressure (highest compared with the lowest quintile of protein intake: ∆=2.4 mm Hg; 95% CI 0.4-4.4; 0.03 for trend). Similar differences, although not significant, were found for systolic blood pressure (∆=2.6 mm Hg; 95% CI -0.0 to 5.3; 0.08 for trend).
Conclusions: Higher maternal dietary protein intake at the expense of carbohydrates was associated with a modest increase in offspring blood pressure in young adulthood.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533044 | PMC |
http://dx.doi.org/10.1161/JAHA.117.005808 | DOI Listing |
J Egypt Public Health Assoc
December 2024
Department of Clinical Nutrition and Dietetics, Faculty of Applied Medical Sciences, The Hashemite University, Zarqa, Jordan.
Background: Metabolic syndrome (MetS) is an important public health issue that has been lately linked as a growing concern worldwide.
The Objective: To find out which anthropometric and body composition indices can prognosticate MetS in Jordanian adult females.
Methods: A sample of 656 Jordanian adult females was recruited (January-March 2024) in the middle of Jordan.
Hipertens Riesgo Vasc
December 2024
Department of Pharmacy Practice, National Institute of Pharmaceutical Education and Research, Hajipur, Bihar, India.
Background: Non-adherence to antihypertensive medication is a key factor contributing to uncontrolled blood pressure and the subsequent complications of hypertension. Despite its importance, there is a lack of data regarding the prevalence of and factors associated with non-adherence to medication among individuals with hypertension in India. This review aimed to assess medication adherence rates among hypertensive patients in India and identify the factors influencing non-adherence.
View Article and Find Full Text PDFZhonghua Yu Fang Yi Xue Za Zhi
December 2024
Children's Hospital Affiliated to Capital Institute of Pediatrics, Beijing100020, China.
This study aimed to analyze the clinical characteristics and prognosis of Takayasu's arteritis (TA) with carotid artery occlusion in children. This study collected clinical data and follow-up information on the first diagnosis and treatment of c-TA combined with carotid artery occlusion in pediatric patients at the Children's Hospital affiliated with the Capital Institute of Pediatrics and Inner Mongolia Medical University Affiliated Hospital from 2013 to 2023. This study included four female patients with a mean age of (13.
View Article and Find Full Text PDFRinsho Shinkeigaku
December 2024
Department of Internal Medicine, Asospa Hospital.
A 61-year-old man with chronic renal failure had an embolic stroke of undetermined source that was treated with warfarin. Five weeks later, the patient contracted coronavirus disease (COVID-19). Six days after the onset of COVID-19, high blood pressure (>200 mmHg) and consciousness disturbance were reported.
View Article and Find Full Text PDFJ Clin Epidemiol
December 2024
Ottawa Hospital Research Institute, Ottawa, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada; Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, Canada; International and Global Health Office, University of Ottawa Faculty of Medicine, Ottawa, Canada; BORN Ontario, Children's Hospital of Eastern Ontario, Ottawa, Canada.
Disease screening aims to identify individuals at risk for specific conditions. It is expected that an early detection allows for early intervention, with improved outcomes. However, large scale screening programs may not only have implications on resources, patient outcomes may not improve but may worsen if screening for the targeted disease has not been carefully designed and executed.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!