Patients commonly present with an acute red eye to the emergency department (ED). It is important to distinguish between benign and sight-threatening diagnoses. Here we provide a comprehensive overview on the acute red eye in the ED.
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http://dx.doi.org/10.5811/westjem.2016.12.31798 | DOI Listing |
Cureus
December 2024
Dermatology, University of California, Davis Medical Center, Sacramento, USA.
Melanonychia describes black pigmentation of the nail plate that results from either melanocyte activation (such as infections, local inflammatory disorders, local trauma affecting the nail plate, numerous systemic conditions, and medications) or melanocyte hyperplasia (such as benign neoplasms or malignant tumors) or blood (resulting from a trauma-associated subungual hematoma). The black dyschromia may include not only the nail plate but also the proximal nailfold. The Hutchinson sign refers to black discoloration of both the proximal nailfold and adjacent nail plate when the underlying pigmented lesion is a malignant melanoma.
View Article and Find Full Text PDFIntroduction: Understanding differences in clinical outcomes between PBSCT and BMT is important, and this study compared outcomes of HLA-matched related PBSCT and BMT using reduced-intensity conditioning (RIC) in adult acute myeloid leukemia (AML) patients.
Methods: Data from 402 patients who underwent either PBSCT ( = 294) or BMT ( = 108) between 2000 and 2022 were analyzed using the Japanese nationwide registry database. The primary endpoint was overall survival (OS), and secondary endpoints included disease-free survival (DFS), non-relapse mortality (NRM), and GVHD.
Gastro Hep Adv
September 2024
Department of Surgery, UTHealth at Houston, Houston, Texas.
Background And Aims: Pancreatic stellate cells (PSCs) are critical mediators in chronic pancreatitis with an undefined role in acute pancreatitis (AP). PSCs consist of a heterogenous group of cells and are considered interchangeable with pancreatic fibroblasts. This study explored the heterogeneous nature of PSCs by characterizing pancreatic collagen-expressing fibroblasts (PCFs) via lineage tracing in mouse normal and AP pancreas and determining the effect of PCF depletion in AP.
View Article and Find Full Text PDFHeliyon
January 2025
Laboratory of Molecular Toxicology, Faculty of Nature and Life Sciences, University of Jijel, 18000, Jijel, Algeria.
has been traditionally used in northeastern Algeria for treating gastrointestinal disorders, particularly ulcers. This study aimed to assess the gastroprotective, anti-inflammatory, and antioxidant properties of a crude hydroalcoholic extract derived from the leaves of , as well as its subsequent fractions. The gastroprotective effect was studied in an ethanol-induced ulcer model in mice.
View Article and Find Full Text PDFJ Trauma Acute Care Surg
February 2025
From the Department of Surgery, Division of Acute Care Surgery, University of Florida College of Medicine (C.A.C.), Gainesville, Florida; Methodist Dallas Medical Center (M.L.), Dallas, Texas; Department of Surgery, Loma Linda University School of Medicine (R.C.), Loma Linda, California; Department of Surgery, Division of Trauma, Acute Care & Critical Care Surgery, Tulane University School of Medicine (J.C.D.), New Orleans, Louisiana; Department of Surgery, Division of Vascular Surgery, University of Maryland School of Medicine (C.F.), Baltimore, Maryland; University of Kansas Medical Center (J.H.), Kansas City, Kansas; Department of Surgery, Division of Emergency General Surgery and Acute Care Surgery, University of Alabama at Birmingham (J.B.H.), Birmingham, Alabama; Department of Surgery, Division of Trauma and Acute Care Surgery, University of Alabama (J.B.H.), Bethesda, Maryland; Department of Surgery, Division of Trauma, Surgical Critical Care and Acute Care Surgery, University of Arizona College of Medicine-Phoenix (N.K.), Phoenix, Arizona; Division of Acute Care Surgery, Department of Surgery (M.J.M., M.S.), Los Angeles General Medical Center, Los Angeles, California; Division of Vascular Surgery and Endovascular Therapy (G.A.M.), Keck Medical Center of USC, Los Angeles, California; Department of Surgery, Division of Acute Care Surgery (L.J.M.), The University of Texas McGovern Medical School-Houston Red Duke Trauma Institute, Memorial Hermann Hospital, Houston, Texas; Department of Surgery, Division of General and Acute Care Surgery, Medical University of South Carolina (A.R.P.), North Charleston, South Carolina; Department of Surgery, Section of General Surgery, Trauma and Surgical Critical Care, Yale School of Medicine (K.M.S.), New Haven, Connecticut; Department of Surgery, Division of Trauma and Acute Care Surgery, UCSF Department of Surgery at Zuckerberg San Francisco General Hospital (R.T.), University of California, San Francisco, San Francisco, California; Department of Surgery, Division of Trauma and Acute Care Surgery, St. Joseph's Hospital and Medical Center (J.A.W.), Phoenix, Arizona; and Program in Trauma (D.M.S), University of Maryland School of Medicine, Baltimore, Maryland.
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