AI Article Synopsis
- The study aimed to evaluate how fluazuron affects pesticide detoxification enzymes in two strains of cattle ticks, one susceptible and one resistant.
- Significant increases in mixed-function oxidases (MFO) and esterases activity were observed in the resistant strain compared to the susceptible strain, particularly in eggs and larvae.
- The findings suggest that detoxification mechanisms in ticks vary with development stages and are linked to resistance against fluazuron.
Article Abstract
The objective of this study was to assess the effect of the exposure to fluazuron on the activity of common pesticide detoxification enzyme groups in the cattle tick (Rhipicephalus microplus). Engorged females of a susceptible strain (POA) and a resistant strain (Jaguar) were exposed in vitro to fluazuron and their eggs and larvae were used to compare the activities of the general esterases, mixed-function oxidases (MFO) and glutathione-S-transferase (GST). The results showed significant elevation in MFO contents and esterases activity in the resistant strain when compared with the susceptible strain, in eggs and larvae respectively. In the POA strain, the MFO activity in eggs was down-regulated by fluazuron exposure. Based on these results, it can be concluded that different detoxification enzymes can act in distinct pathways depending on the tick's development stage, and may be related to fluazuron detoxification in resistant strains.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.parint.2017.04.006 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Starvation Metabolism Adaptations in Tick Embryonic Cells BME26.
Int J Mol Sci
December 2024
Laboratório de Bioquímica de Artrópodes Hematófagos, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-590, Brazil.
Ticks are hematophagous ectoparasites that transmit pathogens and inflict significant economic losses on the cattle industry. Remarkably, they can survive extended periods of starvation in the absence of a host. The primary objective of this study was to investigate the metabolic adaptations that enable the tick to endure starvation using the BME26 cell line as a model system.
View Article and Find Full Text PDFIn Situ Localization of and in Infected Ticks: Implications for Biocontrol Strategies.
Pathogens
November 2024
Centro Nacional de Investigación Disciplinaria en Salud Animal e Inocuidad, Instituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias INIFAP, Boulevard Cuauhnahuac 8534, Jiutepec 62574, Morelos, Mexico.
is a blood-sucking parasite that causes heavy infestations on cattle and is a vector for severe tick-borne diseases, such as anaplasmosis and babesiosis, and poses a significant threat to the cattle industry. Cattle ticks show increasing acaricide resistance, which creates an additional problem concerning the inefficient chemical control of tick populations in cattle-grazing areas, necessitating the exploration of alternative tick biocontrol methods. Our study aimed to demonstrate the acaropathogenic efficacy of two bacterial species during experimental infections on .
View Article and Find Full Text PDFTeratological abnormalities in hard ticks (Acari: Ixodidae) from Pakistan.
Exp Appl Acarol
December 2024
Department of Zoology, Abdul Wali Khan University Mardan, Mardan, 23200, Pakistan.
Studying teratological abnormalities in ticks are taxonomically important because this poorly understood biological phenomenon causes difficulties in tick's identification. Globally, reports regarding these abnormalities in ticks, reasons of their causes and their impacts are scarce. According to the available published data, there are no studies regarding teratological abnormalities in ticks from Pakistan.
View Article and Find Full Text PDFSpatiotemporal heterogeneity of Rhipicephalus microplus resistance to chemical acaricides at intra-farm level: A case study using ivermectin.
Med Vet Entomol
December 2024
Instituto de Investigación de la Cadena Láctea (IdICaL) (INTA-CONICET), Instituto Nacional de Tecnología Agropecuaria, INTA E.E.A. Rafaela, Rafaela, Argentina.
The aim of this work was to analyse the spatiotemporal heterogeneity of Rhipicephalus microplus (Canestrini, 1888) (Acari: Ixodidae) resistance to chemical acaricides at intra-farm level under different environmental (favourable and unfavourable areas for tick development) and management (different schemes of acaricides applications) conditions using ivermectin as a model. The in vitro larval immersion test (LIT) was used to determine quantitatively the levels of resistance to ivermectin in the different populations and subpopulations of R. microplus analysed.
View Article and Find Full Text PDFIdentification and phylogenetic analysis of Jingmen tick virus in ticks and sheep from Henan Province, China.
Virol J
December 2024
Shandong Second Medical University, Weifang, 261053, China.
Jingmen tick virus (JMTV) is a novel segmented Flavivirus that was first identified from Rhipicephalus microplus in the Jingmen region of Hubei Province, China, in 2010. Subsequently, it was detected in a variety of countries and regions around the world. Meanwhile, JMTV has been proved to be pathogenic to humans and animals and could cause viremia in animals.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!