This paper highlights the origins of combined positron emission tomography (PET) and magnetic resonance imaging (MRI) whole-body systems that were first introduced for applications in humans in 2010. This text first covers basic aspects of each imaging modality before describing the technical and methodological challenges of combining PET and MRI within a single system. After several years of development, combined and even fully-integrated PET/MRI systems have become available and made their way into the clinic. This multi-modality imaging system lends itself to the advanced exploration of diseases to support personalized medicine in a long run. To that extent, this paper provides an introduction to PET/MRI methodology and important technical solutions.
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http://dx.doi.org/10.1016/j.ejrad.2017.04.004 | DOI Listing |
External fixation is a powerful tool in orthopaedic trauma surgery. Beyond serving as provisional or temporizing fixation, external fixation has utility as an intraoperative reduction tool, adjunct to internal fixation, and definitive fixation. It is important to summarize the indications, techniques, and considerations of various roles of external fixation in orthopaedic trauma.
View Article and Find Full Text PDFAnal Methods
January 2025
Department of Fundamental Chemistry, LIA3 - Applied Analytical Instrumentation Laboratory, Federal University of Pernambuco, Av. Jornalista Anibal Fernandes, s/n, Cidade Universitária, Recife, PE, 50740-560, Brazil.
This review provides a critical assessment of the most recent advances in digital imaging (DI) methods, applied for the development of analytical methodologies combining quantum dots (QDs). The state-of-the-art, treatment of data, instrumental considerations, software, sensing approaches, and optimization of the resulting methods are reported. Applications of the technology for the analysis of food and beverages, biomedically relevant analytes, drugs, environmental samples and forensic samples are also discussed.
View Article and Find Full Text PDFA A Pract
January 2025
From the Department of Pain Management, Cleveland Clinic, Cleveland, Ohio.
Intercostal neuralgia can be debilitating and extremely difficult to treat despite multi-modal therapies. The literature describing the role of neuromodulation in patients with intercostal neuralgia is scarce. In this medically challenging case report, we describe a 56-year-old male with a near complete resolution of intractable chronic intercostal neuralgia, secondary to traumatic rib fractures and multiple surgical interventions, with a single lead thoracic spinal cord stimulator (SCS) implant.
View Article and Find Full Text PDFNanoscale
January 2025
College of Optical and Electronic Technology, China Jiliang University, Hangzhou 310018, China.
Dynamic surface-enhanced Raman spectroscopy (SERS) is nowadays one of the most interesting applications of SERS, in particular for single molecule studies. In fact, it enables the study of real-time processes at the molecular level. This review summarizes the latest developments in dynamic SERS techniques and their applications, focusing on new instrumentation, data analysis methods, temporal resolution and sensitivity improvements, and novel substrates.
View Article and Find Full Text PDFEur J Anaesthesiol
February 2025
From the Department of Anesthesia, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China (XC, YT, QY, LS, HL, LW, CJ, XC).
Background: Rapid onset of epidural analgesia is an important concern for the parturient. Commonly, the local anaesthetic mixture is administered through the epidural catheter. Drugs administered through the epidural needle might decrease the onset time and enhance the spread of medication within the epidural space.
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