Although extant evidence suggests that many neural and cognitive mechanisms underlying episodic past, future, and counterfactual thinking overlap, recent results have uncovered differences among these three processes. However, the extent to which there may be age-related differences in the phenomenological characteristics associated with episodic past, future and counterfactual thinking remains unclear. This study used adapted versions of the Memory Characteristics Questionnaire and the Autobiographical Interview in younger and older adults to investigate the subjective experience of episodic past, future and counterfactual thinking. The results suggest that, across all conditions, younger adults generated more internal details than older adults. However, older adults generated more external details for episodic future and counterfactual thinking than younger adults. Additionally, younger and older adults generated more internal details, and gave higher sensory and contextual ratings, for memories rather than future and counterfactual thoughts. Methodological and theoretical consequences for extant theories of mental simulation are discussed.
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http://dx.doi.org/10.1016/j.concog.2017.04.007 | DOI Listing |
Soc Sci Med
November 2024
Health Economics Unit, Institute of Applied Health Research, University of Birmingham, UK. Electronic address:
Complex health system questions often have a case study (such as a country) as the unit of analysis. Process tracing, a method from policy studies, is a flexible approach for causal analysis within case studies, increasingly used in applied health research. The aim of this study was to identify the ways in which process tracing methods have been used in health research, and provide insights for best practice.
View Article and Find Full Text PDFJ Mol Graph Model
December 2024
Department of Chemistry, Faculty of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh,11623, Saudi Arabia. Electronic address:
The work being presented now combines severe gradient boosting with Shapley values, a thriving merger within the field of explainable artificial intelligence. We also use a genetic algorithm to analyse the HDAC1 inhibitory activity of a broad pool of 1274 molecules experimentally reported for HDAC1 inhibition. We conduct this analysis to ascertain the HDAC1 inhibitory activity of these molecules.
View Article and Find Full Text PDFEnviron Health Perspect
December 2024
Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Background: While water, sanitation, and hygiene (WASH) interventions can reduce diarrheal disease, many large-scale trials have not found the expected health gains for young children in low-resource settings. Evidence-based guidance is needed to improve interventions and remove barriers to diarrheal disease reduction.
Objectives: We aimed to estimate how sensitive WASH intervention effectiveness was to underlying contextual and intervention factors in the WASH Benefits (WASH-B) Bangladesh cluster-randomized controlled trial.
BMC Glob Public Health
June 2024
School of Public Health, Kunming Medical University, Kunming, Yunnan, People's Republic of China.
Background: Understanding how the COVID-19 pandemic evolved under control measures is crucial to tackle the SARS-CoV-2 virus spread. Laos, a country bordering China but with late occurrence and low burden of COVID-19 compared to its neighbouring countries, was used for a case study.
Methods: A transmission model with disease reporting was proposed to investigate the impact of control measures on the SARS-CoV-2 virus spread in Laos from April 2021 to May 2022.
Int J Epidemiol
December 2024
The Braun School of Public Health and Community Medicine, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Background: There have been reports of sharp declines in acute coronary syndrome (ACS) during the COVID-19 pandemic. The study aims to assess nationwide ACS emergency department (ED) visit rates across age and sex subgroups and the general population, with a comparison before and throughout the pandemic's various phases.
Methods: A multiple interrupted time series analysis was used to assess 61 349 ACS nationwide hospital visits from January 2018 to December 2021 at monthly intervals.
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