The effects of different dopamine concentrations on contractility of myocardium with blocked α- or β-adrenoceptors were examined in vitro in 21- and 100-day old rats. In myocardial strips with blocked α-adrenoceptors, dopamine (10 M) increased the right atrial contractile force. By contrast, this neurotransmitter (10-10 M) reduced the contractile force of atrial and ventricular strips with blocked β-adrenoceptors.
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