AI Article Synopsis
- Narrowband UVB (Nb UVB) therapy is primarily used for conditions like psoriasis and atopic dermatitis but is being evaluated for its effectiveness in treating vitiligo in children.
- In a study involving 26 patients under 18, the results showed that 45.4% had a strong repigmentation response (>75%), indicating that Nb UVB treatment can be beneficial.
- While Nb UVB is generally safe and well-tolerated, potential long-term risks such as skin cancer (photocarcinogenesis) and skin aging (photoaging) need to be considered.
Article Abstract
Background/aim: Narrowband UVB (Nb UVB) treatment is commonly used for the management of psoriasis and atopic dermatitis, and is less often used for vitiligo in children. The aim of this study was to evaluate the efficacy and short-term safety of Nb UVB phototherapy in children diagnosed with vitiligo retrospectively.
Materials And Methods: A total of 26 patients younger than 18 years with the diagnosis of vitiligo and managed with Nb UVB phototherapy as documented in archive records were evaluated. Clinical response was assessed according to repigmentation of the lesions: good response when there was more than 75% repigmentation, moderate response when there was 25%-74% repigmentation, poor response when repigmentation was less than 24%, and unresponsive when there was no pigmentation and new lesions occurred.
Results: A total of 26 patients received Nb UVB treatment; 14 were girls and 12 were boys. The age at onset of the disease varied between 2 and 18 years, with a mean age of onset of 10.07 ± 4.53 years. Repigmentation rate of >75% was detected in 45.4% of cases.
Conclusion: Nb UVB phototherapy seems to be a well-tolerated effective and safe treatment option in children, especially those unresponsive to topical treatment and those with widespread lesions. However, long-term risks such as photocarcinogenesis and photoaging should kept in mind.
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| http://dx.doi.org/10.3906/sag-1512-59 | DOI Listing |
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