[Brodmann Areas 11, 46, and 47: Emotion, Memory, and Empathy].

Brain Nerve

Department of Psychiatry, Graduate School of Medicine, Kyoto University.

Published: April 2017

Brodmann area 11 is one of the main constituent of the orbitofrontal cortex, and area 46 is that of the dorsolateral prefrontal cortex. The main function of Brodmann area 11 is the processing of emotion and value, whereas the main function of Brodmann area 46 is the processing of cognitive information, including working memory. In comparison, the function of area 47 is more complex. This area is related to the feeling of empathy towards the story contents of others, which is thought to be the emotional aspect of this area, while this area is also activated during automated action. This is in contrast with the function of area 46, which is involved in willed action. In addition, area 47 in the left hemisphere plays an important role in syntax processing.

Download full-text PDF

Source
http://dx.doi.org/10.11477/mf.1416200753DOI Listing

Publication Analysis

Top Keywords

brodmann area
12
area
10
main function
8
function brodmann
8
area processing
8
function area
8
[brodmann areas
4
areas emotion
4
emotion memory
4
memory empathy]
4

Similar Publications

Background: Alzheimer's disease (AD) affects over 55 million people worldwide and is characterized by abnormal deposition of amyloid-β and tau in the brain causing neuronal damage and disrupting transmission within brain circuits. Episodic memory loss, executive deficits, and depression are common symptoms arising from altered function in spatially distinct brain circuits that greatly contribute to disability. Transcranial electrical stimulation (tES) can target these circuits and has shown promise to relieve specific symptoms.

View Article and Find Full Text PDF

The role of the left primary motor cortex in apraxia.

Neurol Res Pract

January 2025

Department of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.

Background: Apraxia is a motor-cognitive disorder that primary sensorimotor deficits cannot solely explain. Previous research in stroke patients has focused on damage to the fronto-parietal praxis networks in the left hemisphere (LH) as the cause of apraxic deficits. In contrast, the potential role of the (left) primary motor cortex (M1) has largely been neglected.

View Article and Find Full Text PDF

Transcranial direct current stimulation in patients with depression: An electric field modeling meta-analysis.

J Affect Disord

January 2025

Mondor University Hospitals, INSERM U955, Institut Mondor de La Recherche Biomédicale (IMRB), University of Paris Est Créteil, Équipe Neuropsychiatrie Translationnelle, Créteil, France; NeuroSpin, Neuroimaging Platform, CEA, UNIACT Lab, PsyBrain Team, Saclay, France. Electronic address:

Transcranial Direct Current Stimulation (tDCS) has shown potential in modulating cortical activity and treating depression. Despite its promise, variability in electrode montage configurations and electric field strength across studies has resulted in inconsistent outcomes. Traditional meta-analytic methods assessing the effect of tDCS in depression typically do not compare tDCS montage and the anatomical distribution of electric field, which is a major source of inter-experimental variability.

View Article and Find Full Text PDF

Background: Lewy body diseases, including dementia with Lewy bodies (DLB), are characterized by α-synuclein accumulation, leading to dementia. Previous studies suggest distinct epigenetic and metabolomic profiles in DLB.

Objective: This study aims to identify diagnostic biomarkers by analyzing the methylome and metabolome in the Brodmann area 7 of postmortem brain tissues from DLB patients and control subjects using multiomics approaches.

View Article and Find Full Text PDF

Background: The relationship between subregion atrophy in the entire temporal lobe and subcortical nuclei and cognitive decline at various stages of Alzheimer's disease (AD) is unclear.

Methods: We selected 711 participants from the AD Neuroimaging Initiative (ADNI) database, which included 195 cases of cognitively normal (CN), 271 cases of early Mild cognitive impairment (MCI) (EMCI), 132 cases of late MCI (LMCI), and 113 cases of AD. we looked at how subregion atrophy in the temporal lobe and subcortical nuclei correlated with cognition at different stages of AD.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!