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Development of a Health-State Classification System for the Pediatric Quality-of-Life Inventory Version 4.0 Generic Core Scales for Preference-Based Valuation in Australia.
Value Health
September 2024
Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, England, UK.
Objectives: Pediatric Quality-of-Life Inventory Version 4.0 Generic Core Scales (PedsQL GCS), comprising 23 items covering 4 subscales (physical, emotional, social, and school functioning), is a widely applied generic measure of childhood health-related quality of life but does not provide health utilities for cost-effectiveness-based decision making. This study aimed to develop a reduced item version of PedsQL GCS amenable to health utility derivation in Australia.
View Article and Find Full Text PDFPatient, Parental, and Health Professional Perspectives on Growth in Children With CKD.
Am J Kidney Dis
January 2025
Sydney School of Public Health, University of Sydney, Sydney, Australia; Centre for Kidney Research, Children's Hospital at Westmead, Sydney, Australia.
Rationale & Objective: Growth failure is a common problem among children with chronic kidney disease (CKD). Reduced height is associated with psychosocial burden, social stigma, and impaired quality of life. This study describes the aspects of growth impairment that are most impactful from the perspectives of children with CKD, their parents, and health professionals.
View Article and Find Full Text PDFA review on mechanistic aspects of litchi fruit induced acute encephalopathy.
Toxicon
September 2024
Department of Biological Sciences (Regulatory Toxicology), National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad, Telangana, 500037, India. Electronic address:
Article Synopsis
- Litchi (Litchi sinensis) is a sweet fruit popular in Southeast Asia but can cause acute encephalopathy syndrome (AES) in malnourished children during its harvest season (May-June), leading to severe health issues like seizures and coma.
- The outbreak of AES is linked to non-protein amino acids, hypoglycine A (HGA) and methylenecyclopropylglycine (MCPG), which interfere with metabolic processes, especially in undernourished children who often eat litchis on an empty stomach.
- Preventive measures include raising awareness about the dangers of consuming litchi while fasting, improving agricultural practices, and ensuring access to glucose to mitigate the
Socio-economic aspects and farming practices of goats in Southern Tunisia.
Trop Anim Health Prod
July 2024
Laboratoire d'Elevage et de la Faune Sauvage-LR16IRA04, Institution de la Recherche et de l'Enseignement Supérieur Agricoles, Arid Regions Institute, University of Gabès, Gabès, Tunisia.
This study aims to describe socio-economic aspects, farming practices and production limitations of goats by surveying 53 farms holding 5507 head in the regions of Tataouine-Tunisia. It was revealed that goats represented a major source of income for most of the producers (66.1%).
View Article and Find Full Text PDFSelecting PedsQL items to derive the PedsUtil health state classification system to measure health utilities in children.
Health Qual Life Outcomes
July 2024
Department of Health Management and Policy, Michigan School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Background: There is a lack of preference-based health-related quality of life (HRQoL) measures that consistently value health across a full range of child age groups. The PedsQL is a generic HRQoL instrument validated for children 2-18 years, but it is not preference-based. The objective of this study was to derive the PedsUtil health state classification system from the PedsQL as a basis for a preference-based HRQoL measure for children.
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