AI Article Synopsis
- Schizophrenia is a chronic mental illness that recurs frequently and significantly impacts society, with diagnosis relying on specific symptoms and disease progression.
- Near-infrared spectroscopy (NIRS) is a technique that measures brain function by assessing hemoglobin concentration changes in the brain's surface areas.
- In a case study of a 17-year-old woman with first-episode schizophrenia, NIRS showed increased cerebral blood volume after treatment, suggesting it could serve as a potential marker for the severity of the illness.
Article Abstract
The clinical course of schizophrenia is characterized by recurrence and chronicity and has a large burden on society. Nevertheless, diagnosis of schizophrenia is based only on distinctive symptoms and the disease course. Near-infrared spectroscopy (NIRS) is a useful method for measuring changes in the hemoglobin concentration in the cortical surface area and reflects brain function. We measured NIRS four times during the clinical course in a patient with first-episode schizophrenia.A 17-year-old woman admitted to our hospital because of hallucinations, delusions and appetite loss. After treatment with low-dose antipsychotics, NIRS findings showed a prompt increase in the cerebral blood volume in the frontal region. On the basis of the clinical course of this patient, we introduce a new point of view, namely, that NIRS findings may be useful as a state marker that indicates the severity of schizophrenia in some cases.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476820 | PMC |
| http://dx.doi.org/10.5387/fms.2016-22 | DOI Listing |
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