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Guidelines for Patient-Centered Documentation in the Era of Open Notes: Qualitative Study.
JMIR Med Educ
January 2025
Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Background: Patients in the United States have recently gained federally mandated, free, and ready electronic access to clinicians' computerized notes in their medical records ("open notes"). This change from longstanding practice can benefit patients in clinically important ways, but studies show some patients feel judged or stigmatized by words or phrases embedded in their records. Therefore, it is imperative that clinicians adopt documentation techniques that help both to empower patients and minimize potential harms.
View Article and Find Full Text PDFSafety, Tolerability, and Pharmacokinetics of a Novel Anti-obesity Agent, S-309309, in Healthy Adults with or Without Obesity.
Clin Drug Investig
January 2025
Medical Science Department, Shionogi & Co., Ltd., Osaka, Japan.
Background: Anti-obesity medications are recommended for patients who do not achieve and maintain weight loss despite lifestyle interventions. S-309309 is a novel oral inhibitor of monoacylglycerol O-acyltransferase 2 being developed as a treatment for obesity.
Objective: The objective of the study was to investigate the safety, clinical pharmacology, pharmacokinetics and pharmacodynamic biomarker of S-309309.
Predictive value of enhanced corneal biomechanical parameters for ectasia progression.
Jpn J Ophthalmol
January 2025
Department of Ophthalmology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Purpose: To determine whether corneal biomechanical parameters can predict ectasia progression.
Study Design: Retrospective observational study.
Methods: The baseline corneal biomechanical parameters of 64 eyes of 41 young patients (age, < 25 years at the first visit) who were diagnosed with keratoconus (KC) or suspected KC at Osaka University Hospital and followed up for more than two years were reviewed.
Hepatopulmonary syndrome from liver disease associated with autosomal recessive polycystic kidney disease.
Pediatr Nephrol
January 2025
Department of Paediatric Nephrology, The Royal Children's Hospital, Melbourne, Australia.
Hepatopulmonary syndrome (HPS) is a life-threatening complication of chronic liver disease (CLD) that currently can be managed only by liver transplant. Though uncommon, some children with kidney disease have coexistent CLD and hence are at risk of developing HPS. Paediatric cases of HPS are rarely described in the nephrology literature.
View Article and Find Full Text PDFSurfactant-based interface capture towards the development of 2D-printed photonic structures.
Mater Horiz
January 2025
Soft Matter Lab, Department of Chemical Engineering, Shiv Nadar Institution of Eminence Deemed to be University, Greater Noida, 201314, India.
This study focuses on fabricating photonic crystals (PCs) by surfactant-based particle capture at the gas-liquid interface of evaporating sessile droplets. The captured particles form interfacial films, resulting in ordered monolayer depositions manifesting iridescent structural colors. The particle dynamics behind the ordered arrangement is delineated.
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