Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Pregnancy occurring in AA amyloidosis: a series of 27 patients including 3 new French cases.
J Nephrol
December 2024
Department of Internal Medicine, Centre de référence des maladies autoinflammatoires et des amyloses (CEREMAIA), DMU i3d, AP-HP, Hôpital Tenon, Service de Médecine Interne, Sorbonne University, Tenon Hospital, 75020, Paris, France.
Article Synopsis
- AA amyloidosis (AAA) is a serious multisystem disease stemming from chronic inflammation, commonly affecting the kidneys and posing risks during pregnancy.
- A study reviewed cases of AAA in pregnant women, identifying three new patients and highlighting that familial Mediterranean fever was the leading cause of AAA in this group.
- The research found that pregnancies in AAA patients often led to complications like growth retardation and preterm birth, indicating the need for heightened medical monitoring during pregnancy.
Plasma AGE and Oxidation Products, Renal Function, and Preeclampsia in Pregnant Women with Type 1 Diabetes: A Prospective Observational Study.
J Diabetes Res
August 2023
Division of Endocrinology, Medical University of South Carolina, Charleston, South Carolina, USA.
Aims: We aimed to determine whether plasma advanced glycation end products or oxidation products (AGE/oxidation-P) predict altered renal function and/or preeclampsia (PE) in pregnant women with type 1 diabetes.
Methods: Prospectively, using a nested case-control design, we studied 47 pregnant women with type 1 diabetes, of whom 23 developed PE and 24 did not. Nineteen nondiabetic, normotensive pregnant women provided reference values.
Oxidative stress reduces trophoblast FOXO1 and integrin β3 expression that inhibits cell motility.
Free Radic Biol Med
August 2018
Department of Medical Research, MacKay Memorial Hospital, 92 Section 2 Zhong-Shan North Road, Taipei 104, Taiwan.
Preeclampsia is a serious pregnancy complication associated with placental oxidative stress and impaired trophoblast migration. The mechanism of defective trophoblast migration remains unknown. Forkhead box O1 (FOXO1) is a transcription factor.
View Article and Find Full Text PDFPredicting the Risk to Develop Preeclampsia in the First Trimester Combining Promoter Variant -98A/C of LGALS13 (Placental Protein 13), Black Ethnicity, Previous Preeclampsia, Obesity, and Maternal Age.
Fetal Diagn Ther
October 2018
Hy Laboratories, Rehovot, Israel.
Article Synopsis
- LGALS13 promoter DNA polymorphisms were researched to see if they can predict preeclampsia (PE), as this protein plays a role in regulating blood pressure, blood vessel growth, and immune response.
- First-trimester plasma samples from PE cases and controls were analyzed through DNA extraction and sequencing, and a luciferase assay was used to measure the expression of different genotypes in specific cell lines.
- The study found that the A/A genotype was more common in the PE group and had a significantly higher risk of developing PE, while the C/C and A/C genotypes appeared to offer some protection, indicating that understanding these genetic variations could help predict PE risk early in pregnancy.
Stent graft types for endovascular repair of abdominal aortic aneurysms.
Cochrane Database Syst Rev
September 2015
iHOPE: International Collaboration to Harmonise Outcomes for Pre-eclampsia, Balliol College, University of Oxford, Oxford, Oxfordshire, UK, OX2 6NW.
Background: The UK prevalence of abdominal aortic aneurysm (AAA) is estimated at 4.9% in over 65-year olds. Progressive and unpredictable enlargement can lead to rupture.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!