AI Article Synopsis
- * It highlights the potential of using stem cells and cochlear gene therapy as promising short-term solutions for hearing loss due to aging.
- * The review aims to enhance understanding of inner ear aging processes and guides future research towards developing effective treatments for age-related hearing impairments in humans.
Article Abstract
The objective of this paper is to review current information regarding the treatment of age-related hearing loss by using cochlear hair cell regeneration. Recent advances in the regeneration of the inner ear, including the usefulness of stem cells, are also presented. Based on the current literature, cochlear cell regeneration may well be possible in the short term and cochlear gene therapy may also be useful for the treatment of hearing loss associated with ageing. The present review provide further insight into the pathogenesis of Inner Ear senescence and aged-related hearing loss and facilitate the development of therapeutic strategies to repair hair cells damaged by ageing. More research will be needed in order to translate them into an effective treatment for deafness linked to cochlear senescence in humans.
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| http://dx.doi.org/10.1016/j.arr.2017.04.002 | DOI Listing |
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