Surgical management of bronchopulmonary carcinoids: A single center experience.

South Asian J Cancer

Department of Surgical Oncology, Dr. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.

Published: January 2017

Introduction: Bronchopulmonary carcinoids are uncommon tumors with relatively indolent biological behavior but a distinct malignant potential. Surgery is the mainstay of treatment. Our aim was to study preoperative characteristics, surgical approaches, and outcome in patients with bronchopulmonary carcinoid tumors.

Patients And Methods: This retrospective study was done in the Department of Surgical Oncology of a Tertiary Teaching Hospital of North India. The case records of all the patients who underwent surgical treatment for lung neoplasms and were diagnosed to have bronchopulmonary carcinoids were reviewed. Details concerning the clinical presentation, preoperative therapy, operative procedure, postoperative complications, and outcome were retrieved from the case records.

Results: Sixteen patients who underwent surgical treatment were found to have bronchopulmonary carcinoids on histopathological examination. The median age of the patients was 34 years (range 18-62 years). There were 11 men and five women. All patients were symptomatic, and the median duration of symptoms was 12 months (range 6-72 months) before presentation. Six patients had received antitubercular treatment before presentation, and one patient had been treated with chemotherapy due to misdiagnosis. Surgical procedures included six pneumonectomies (one with carinoplasty), four bilobectomies, three lobectomies, and three bronchoplastic procedures (two with lobectomy and one with bilobectomy). There was no postoperative mortality; three patients had morbidity in the form of lobar collapse, prolonged pleural collection, and surgical site infection. With a median follow-up time of 11 months (range 2-85 months), all the 16 patients are alive and disease-free.

Conclusions: Delayed presentation and misdiagnosis of bronchial carcinoid are major concerns in North India. Adequate surgical resection can be performed without undue morbidity and is associated with good long-term results.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379900PMC
http://dx.doi.org/10.4103/2278-330X.202568DOI Listing

Publication Analysis

Top Keywords

bronchopulmonary carcinoids
16
surgical
8
patients
8
north india
8
patients underwent
8
underwent surgical
8
surgical treatment
8
months range
8
bronchopulmonary
5
surgical management
4

Similar Publications

Introduction: Lung cancer is a major cause of cancer-related deaths, with 2 million new cases annually. Bronchopulmonary neuroendocrine tumors (BP-NETs) comprise about 20 % of lung cancers, including typical carcinoid tumors (TC). While tobacco is a primary risk factor, non-tobacco factors also play a role.

View Article and Find Full Text PDF

Central nervous system (CNS) metastases of atypical carcinoid tumors are exceptionally rare. Isolated studies suggest a survival benefit in patients who receive whole-brain radiotherapy (WBRT); however, it has been known to have detrimental effects on long-term memory and executive function. Here, we present a case of a patient initially diagnosed with stage IIB bronchopulmonary carcinoid who later developed hepatic and intracranial metastases despite receiving adjuvant systemic therapy over a two-year period.

View Article and Find Full Text PDF

The role of wedge resection and lymph node examination in stage IA lung carcinoid tumors.

J Thorac Dis

September 2024

Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Article Synopsis
  • Researchers analyzed data from a large group of patients who had different resection types and categorized them based on lymph node examination to assess overall survival rates.
  • The findings suggest that wedge resection provides similar survival rates to anatomical resection for early-stage carcinoids, and that examining lymph nodes significantly enhances survival outcomes.
View Article and Find Full Text PDF

Diagnostic issues in neuroendocrine neoplasms of the lung.

Pathologie (Heidelb)

November 2024

Department of Pathology, TUM School of Medicine and Health, Trogerstr. 18, 81675, Munich, Germany.

Article Synopsis
  • Bronchopulmonary neuroendocrine neoplasms (BP-NENs) make up about 30% of all neuroendocrine neoplasms (NENs) and show similarities to gastroenteropancreatic NENs (GEP-NENs) but differ in classification.
  • BP-NETs (previously known as carcinoids) are classified into typical (TC) and atypical carcinoids (AC), with the new WHO 2022 classification introducing NET G1 and G2 correspondingly.
  • The review emphasizes the significance of the Ki-67 index for accurately classifying BP-NETs, noting that it is not included in their current classification criteria despite its relevance in
View Article and Find Full Text PDF

Background: Bronchopulmonary carcinoid tumors include typical and atypical carcinoids, with typical carcinoids accounting for 80%-90% of these types of tumor. The primary curative treatment for these tumors is surgical resection. To our knowledge, there are limited studies on the presentation patterns and treatment strategies of bronchopulmonary carcinoid tumors in Africa.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!