Therapeutic Inhibition of Complement: Well Worth the Risk.

Trends Pharmacol Sci

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address:

Published: June 2017

Complement is an integral part of the immune system and protects against infection. Complement-mediated immunopathology in many autoimmune diseases and syndromes has led to the therapeutic targeting of complement and to questions around the safety of complement inhibition. Here; I examine and clarify the risks associated with complement therapeutics.

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Source
http://dx.doi.org/10.1016/j.tips.2017.03.009DOI Listing

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