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Pre- and post-diagnosis body weight trajectories in patients with localized renal cell cancer.
Cancer Causes Control
January 2025
IQ Health Science Department, Radboud University Medical Center, Nijmegen, The Netherlands.
Purpose: Obesity in mid-life is a well-established risk factor for developing renal cell carcinoma (RCC); however, patients with RCC who are obese at the time of diagnosis have more favorable survival outcomes. To get better insight into the obesity paradox and determine the extent to which weight around diagnosis is stable, we examined pre- and post-diagnosis weight changes in patients with localized RCC.
Methods: We included 334 patients with localized RCC from the prospective cohort ReLife who self-reported body weight at multiple time points ranging from 2 years before to 2 years after diagnosis.
Prognostic significance of body mass index in patients with metastatic renal cell carcinoma receiving first-line therapies.
Urol Oncol
January 2025
Department of Genitourinary Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Objectives: Higher body mass index (BMI) is reportedly associated with improved prognosis of patients with various cancers. However, it is unclear whether this phenomenon, also known as the obesity paradox, applies to metastatic renal cell carcinoma (mRCC). We aimed to determine the prognostic significance of BMI in patients with mRCC receiving first-line therapies.
View Article and Find Full Text PDFThe impact of body mass index on surgical complications in minimally invasive hysterectomy for uterine fibroids.
Eur J Obstet Gynecol Reprod Biol
December 2024
Department of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Ramat-Gan, Israel; The School of Medicine, Tel Aviv University, Israel; Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology, Cedars Sinai Medical Center, Los Angeles, CA, United States; The Dr. Pinchas Bornstein Talpiot Medical Leadership Program, Sheba Medical Center, Tel Hashomer, Ramat-Gan, Israel.
Research Question: We aimed to assess the impact of Body Mass Index (BMI) on 30-day postoperative complications in patients undergoing minimally invasive hysterectomy (MIH) for fibroids.
Design: Using data from the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database (2012-2020), we analyzed major and minor 30-day postoperative complications, stratified by BMI, in patients with uterine fibroids who underwent MIH. Complications were stratified according to the Clavien-Dindo classification.
Association of body mass index with clinicopathological features among patients with clear cell renal cell carcinoma treated with surgery: a retrospective study.
Sci Rep
January 2025
Department of Urology, Changhai Hospital, Naval Medical University, Shanghai, 200433, China.
To investigate the potential association between body mass index (BMI) and the clinicopathological features of patients with clear cell renal cell carcinoma (ccRCC). We retrospectively analyzed data from 2541 patients who underwent partial or radical nephrectomy for renal masses between 2013 and 2023 in a single institution. Patients were divided into normal-weight, overweight, and obese groups based on the Chinese BMI classification.
View Article and Find Full Text PDFObesity in the US: Exploring the paradox of increasing obesity rates alongside growing physical activity.
Obes Res Clin Pract
December 2024
Faculty of Data Science, Musashino University, 3-3-3 Ariake Koto-ku, Tokyo 135-8181, Japan. Electronic address:
The study analyzes a CDC dataset on US adult obesity and physical activity from 2011 to 2022. Despite rising obesity rates and insufficient fruit consumption, physical activity levels are increasing and overweight rates are slightly declining. The role of ultra-processed food intake, price sensitivity, early eating habits, and stress in obesity is highlighted.
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