AI Article Synopsis

  • Positional therapy is a simple yet controversial treatment for sleep apnoea, specifically for patients with supine-exclusive sleep apnoea syndrome.
  • Approximately 105 out of 112 patients evaluated received this therapy, with 75% initially achieving a low Apnoea-Hypopnoea Index (AHI), though long-term adherence dropped to 32% after one year.
  • The study found that Body Mass Index (BMI) was a significant predictor for successful AHI reduction, but other factors like sex and severity of sleep apnoea did not influence success rates.

Article Abstract

Introduction: Positional therapy is a simple means of therapy in sleep apnoea syndrome, but due to controversial or lacking evidence, it is not widely accepted as appropriate treatment. In this study, we analysed data to positional therapy with regard to successful reduction of AHI and predictors of success.

Methods: All consecutive patients undergoing polysomnography between 2007 and 2011 were analysed. We used a strict definition of positional sleep apnoea syndrome (supine-exclusive sleep apnoea syndrome) and of therapy used. Patients underwent polysomnography initially and during follow-up.

Results: 1275 patients were evaluated, 112 of which had supine-exclusive sleep apnoea syndrome (AHI 5-66/h, median 13/h), 105 received positional therapy. With this treatment alone 75% (70/105) reached an AHI <5/h, in the follow-up 1 year later 37% (37/105) of these still had AHI<5/h, 46% (43/105) yielded an AHI between 5 and 10/h. Nine patient switched to APAP due to deterioration, 3 wanted to try APAP due to comfort reasons. At the last follow-up, 32% patients (34/105) were still on positional therapy with AHI <5/h. BMI was a predictor for successful reduction of AHI, but success was independent of sex, the presence of obstructive versus central sleep apnoea, severity of sleep apnoea syndrome or co-morbidities.

Conclusion: Positional therapy may be a promising therapy option for patients with positional sleep apnoea. With appropriate adherence it yields a reasonable success rate in the clinical routine.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390972PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0174468PLOS

Publication Analysis

Top Keywords

sleep apnoea
24
positional therapy
20
apnoea syndrome
20
therapy sleep
12
supine-exclusive sleep
8
positional
6
sleep
6
apnoea
6
therapy
6
syndrome
5

Similar Publications

European central hypoventilation syndrome consortium description of congenital central hypoventilation syndrome neonatal onset.

Eur J Pediatr

January 2025

Service de Physiologie Pédiatrique-Centre du Sommeil-CRMR Hypoventilations Alvéolaires Rares, INSERM NeuroDiderot, Université Paris-Cité, AP-HP, Hôpital Robert Debré, Paris, France.

Unlabelled: It is known that in most cases of congenital central hypoventilation syndrome (CCHS), apnoeas and hypoventilation occur at birth. Nevertheless, a detailed description of initial symptoms, including pregnancy events and diagnostic tests performed, is warranted in infants with neonatal onset of CCHS, that is, in the first month of life. The European Central Hypoventilation Syndrome Consortium created an online patient registry from which 97 infants (44 females) with CCHS of neonatal onset and PHOX2B mutation from 10 countries were selected.

View Article and Find Full Text PDF

Objective: Patients with obstructive sleep apnea (OSA) frequently suffer from migraine, however the causal relationship between OSA and migraine is unknown. Investigating the causation will assist in understanding the etiology of OSA and migraine.

Methods: Bidirectional two-sample Mendelian randomization (MR) and multivariable MR (MVMR) approaches were carried out to investigate the causal link between OSA and migraine.

View Article and Find Full Text PDF

Development and Evaluation of a Hypertension Prediction Model for Community-Based Screening of Sleep-Disordered Breathing.

Nat Sci Sleep

January 2025

Sleep Center, Department of Geriatric Respiratory, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, People's Republic of China.

Purpose: Approximately 30% of patients with sleep-disordered breathing (SDB) present with masked hypertension, primarily characterized by elevated nighttime blood pressure. This study aimed to develop a hypertension prediction model tailored for primary care physicians, utilizing simple, readily available predictors derived from type IV sleep monitoring devices.

Patients And Methods: Participants were recruited from communities in Guangdong Province, China, between April and May 2021.

View Article and Find Full Text PDF

Background: Interleukin-6 (IL-6) represents one of the main molecules involved in inflammatory responses, which can be altered in either patients with cognitive impairment or obstructive sleep apnea (OSA). The present study aimed to evaluate serum IL-6 levels and cognitive performance in patients with severe OSA (Apnea-Hypopnea Index - AHI >30/h).

Methods: Thirty patients with severe OSA were compared to 15 controls similar in age, sex, and Body Mass Index.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!