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EVALUATION OF ETORPHINE-MEDETOMIDINE-MIDAZOLAMAZAPERONE FOR IMMOBILIZATION IN CAPTIVE PRONGHORN ().

J Zoo Wildl Med

December 2024

Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, S7N 5B4, SK, Canada.

Etorphine based immobilization protocols are reported to be effective in pronghorn; however, information on cardiorespiratory effects is limited. The objective of this study was to evaluate the efficacy and cardiopulmonary effects of etorphine, medetomidine, midazolam, and azaperone for immobilization in captive pronghorn. Additionally, the effects of endotracheal intubation and manual ventilation on cardiopulmonary variables were assessed.

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A review of perioperative mortality in pet rabbits in Australia.

Aust Vet J

November 2024

The Unusual Pet Vets, Frankston, Victoria, Australia.

Article Synopsis
  • Domestic rabbits have a higher perioperative mortality rate (2.05%) compared to dogs and cats, mainly due to cardiovascular and respiratory complications, making understanding anaesthetic risks crucial.
  • Data from 1,757 rabbits undergoing anaesthesia revealed that poorer health status (ASA score), non-routine procedures, and certain physical traits (like being under 1 kg or a Netherland Dwarf breed) significantly increased mortality risks.
  • Using a supraglottic airway device was found to lower mortality risk compared to endotracheal tubes or masks, and a medetomidine-based anaesthetic protocol was safer than one based on fentanyl.
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Article Synopsis
  • * Dogs receiving the medetomidine-vatinoxan experienced lower mean arterial pressures (MAP) that stabilized at 102-104 mmHg, while those on medetomidine alone had significantly higher MAPs of 143-126 mmHg.
  • * Heart rate (HR) remained stable in the medetomidine-vatinoxan group, whereas it dropped significantly in the medetomidine group, suggesting that vatinoxan could be beneficial in preventing bradycardia and managing systemic pressure during anesthesia in dogs.
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Article Synopsis
  • - The study aimed to determine how different sedation protocols (MVH, DH, H) affected the amount of alfaxalone needed for anesthesia in healthy Beagle dogs and to assess various cardiopulmonary metrics.
  • - In this experiment, dogs premedicated with MVH required less alfaxalone for induction compared to those given DH or H and experienced a higher incidence and duration of hypotension during anesthesia.
  • - The findings suggest that while MVH is effective for reducing alfaxalone dosage, it may lead to significant drops in arterial pressure, indicating a trade-off in its clinical use.
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Butorphanol-azaperone-medetomidine (BAM) is commonly used for white-tailed deer (Odocoileus virginianus) immobilization in captive and free-ranging populations. It is a federally regulated controlled substance requiring stringent regulatory compliance, complicating field application. A prescription-only drug combination, nalbuphine-medetomidine-azaperone® (NalMed-A) provides a less-regulated alternative for use by wildlife professionals.

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