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Latin America's Dengue Outbreak Poses a Global Health Threat.
Viruses
January 2025
Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 5508-900, Brazil.
Dengue fever, caused by the dengue virus (DENV), poses a significant global health challenge, particularly in tropical and subtropical regions. Recent increases in indigenous DENV cases in Europe are concerning, reflecting rising incidence linked to climate change and the spread of mosquitoes. These vectors thrive under environmental conditions like temperature and humidity, which are increasingly influenced by climate change.
View Article and Find Full Text PDFEstimation and Characterization of Dengue Serotypes in Patients Presenting with Dengue Fever at Makkah Hospitals.
Trop Med Infect Dis
January 2025
Department of Research, PMO, Ministry Branch in Makkah Region, Ministry of Health (MOH), Makkah 21955, Saudi Arabia.
Dengue fever is caused by four common serotypes of the dengue virus (DENV-1, DENV-2, DENV-3, and DENV-4). Patients infected with one serotype may develop lifelong serotype-specific protective immunity. However, they remain susceptible to reinfection with the other serotypes, often increasing the risk of severe forms of dengue.
View Article and Find Full Text PDFDevelopment of nucleic acid-based vaccines against dengue and other mosquito-borne flaviviruses: the past, present, and future.
Front Immunol
January 2025
Infectious Disease Research Department, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University of Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
Due to their widespread geographic distribution and frequent outbreaks, mosquito-borne flaviviruses, such as DENV (DENV), Zika virus (ZIKV), Japanese encephalitis virus (JEV), yellow fever virus (YFV), and West Nile virus (WNV), are considered significant global public health threats and contribute to dramatic socioeconomic imbalances worldwide. The global prevalence of these viruses is largely driven by extensive international travels and ecological disruptions that create favorable conditions for the breeding of and species, the mosquito vectors responsible for the spread of these pathogens. Currently, vaccines are available for only DENV, YFV, and JEV, but these face several challenges, including safety concerns, lengthy production processes, and logistical difficulties in distribution, especially in resource-limited regions, highlighting the urgent need for innovative vaccine approaches.
View Article and Find Full Text PDFEvaluating the effectiveness of dengue surveillance in the tropical and sub-tropical Asian nations through dengue case data from travelers returning to the five Western Pacific countries and territories.
Travel Med Infect Dis
January 2025
Department of Environmental Biology and Medical Parasitology, College of Medicine, Hanyang University, Seoul, Republic of Korea. Electronic address:
Introduction: Dengue, affecting over 3.9 billion people, is a significant health threat globally. Despite a tenfold increase in reported cases from 2000 to 2020, underreporting remains an issue.
View Article and Find Full Text PDFHantavirus and Leptospira are important causes of nonspecific acute febrile syndrome, Meta, Colombia.
Travel Med Infect Dis
January 2025
Universidad Cooperativa de Colombia, Facultad de Medicina. Grupo de investigación de Villavicencio-GRIVI, y Centro de Investigación en Salud para el Trópico. Electronic address:
Introduction: Acute undifferentiated febrile illnesses are fevers lasting less than fourteen days without an evident focus of infection on the initial physical examination or with inconclusive laboratory tests.
Objective: Carry out epidemiological surveillance of the etiology of acute undifferentiated febrile syndrome in the Meta department.
Methods: A descriptive, prospective cross-sectional study was carried out between February 2021 and June 2023 in a first-level hospital in the department of Meta, Colombia.
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