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Approach to skin problems in travellers: clinical and epidemiological clues.
J Travel Med
December 2024
Infectious and Tropical Diseases, Sorbonne University, Faculté de médecine, Hôpitaux Universitaires Pitié Salpêtrière, Boulevard de l'Hôpital, 75013, Paris, France.
Article Synopsis
- Travelers often experience skin problems requiring medical attention, with proper diagnosis relying on clinical examinations and understanding travel history and behaviors.* -
- The most common travel-related skin issues include insect bites, sunburns, and infections like hookworm and bacteria, with specific diseases like dengue fever and schistosomiasis being noteworthy.* -
- Evaluating skin conditions involves considering travel history, activities, and specific lesion characteristics, which help identify risks and guide treatment.*
Combination Therapy and Phytochemical-Loaded Nanosytems for the Treatment of Neglected Tropical Diseases.
Pharmaceutics
September 2024
Section for Postgraduate Studies and Research, Escuela Nacional de Medicina y Homeopatía, Instituto Politécnico Nacional, Guillermo Massieu Helguera #239, Fracc. La Escalera, Ticomán, Ciudad de México 07320, Mexico.
Neglected tropical diseases (NTDs), including leishmaniasis, trypanosomiasis, and schistosomiasis, impose a significant public health burden, especially in developing countries. Despite control efforts, treatment remains challenging due to drug resistance and lack of effective therapies. : This study aimed to synthesize the current research on the combination therapy and phytochemical-loaded nanosystems, which have emerged as promising strategies to enhance treatment efficacy and safety.
View Article and Find Full Text PDFMrgprA3 neurons drive cutaneous immunity against helminths through selective control of myeloid-derived IL-33.
Nat Immunol
November 2024
Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Skin uses interdependent cellular networks for barrier integrity and host immunity, but most underlying mechanisms remain obscure. Herein, we demonstrate that the human parasitic helminth Schistosoma mansoni inhibited pruritus evoked by itch-sensing afferents bearing the Mas-related G-protein-coupled receptor A3 (MrgprA3) in mice. MrgprA3 neurons controlled interleukin (IL)-17 γδ T cell expansion, epidermal hyperplasia and host resistance against S.
View Article and Find Full Text PDFSchistosomiasis in migrant children and adolescents in a paediatric tropical referral unit in Spain: diagnosis and long-term management challenges.
Eur J Pediatr
October 2024
General Paediatrics, Infectious and Tropical Diseases Department, Hospital La Paz, Madrid, Spain.
Globalisation and population movement have led to an increasing number of migrant children residing in areas non-endemic for schistosomiasis. However, diagnosing and managing schistosomiasis in children remain controversial. This study aims to investigate the prevalence of schistosomiasis in migrant children and to describe the diagnostic approach and management strategies, including long-term follow-up, to explore the potential role of serological tests in evaluating treatment response.
View Article and Find Full Text PDFIntramedullary spinal schistosomiasis: A case report and review of the literature.
Int J Surg Case Rep
September 2024
Department of Pathology, Specialties Hospital, Ibn Sina university Hospital, Rabat 12000, Morocco; Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco.
Introduction: Spinal cord schistosomiasis is an extremely rare entity presenting with a wide range of neurological symptoms. The early diagnosis and treatment can improve neurological outcome. Histopathological examination is the gold standard for establishing the diagnosis of spinal schistosomiasis, revealing schistosoma eggs.
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