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Prevalence of Cryptosporidium Carriage and Disease in Children With Primary Immune Deficiencies Undergoing Hematopoietic Stem Cell Transplant in Northern Europe. | LitMetric
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Prevalence of Cryptosporidium Carriage and Disease in Children With Primary Immune Deficiencies Undergoing Hematopoietic Stem Cell Transplant in Northern Europe.

Angharad P Davies Mary Slatter Andrew R Gennery Guy Robinson Nigel Crouch Kristin Elwin Stephen J Hadfield Andrew J Cant E Graham Davies Rachel M Chalmers

Pediatr Infect Dis J

From the *Swansea University Medical School, Singleton Park, Swansea, United Kingdom; †Cryptosporidium Reference Unit, Public Health Wales Microbiology Swansea, Singleton Hospital, Sketty Lane, Swansea, United Kingdom; ‡Paediatric Immunology Department, Great North Children's Hospital, Queen Victoria Road, Newcastle upon Tyne, United Kingdom; §Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; and ¶Centre for Immunodeficiency, Institute of Child Health, University College London and Great Ormond Street Hospital, London, United Kingdom.

Published: May 2017

A prospective cohort study of children with primary immunodeficiencies undergoing hematopoietic stem cell transplant in the United Kingdom investigated the extent and significance of Cryptosporidium carriage in this high risk group. Three of 42 children recruited were infected with Cryptosporidium, a lower proportion than previously described. One had serious disease. The underlying immunodeficiency likely had a bearing on the clinical presentation and possible outcome of infection.

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 Source
http://dx.doi.org/10.1097/INF.0000000000001517DOI Listing

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