One-step colorimetric detection of an antibody based on protein-induced unfolding of a G-quadruplex switch.

Chem Commun (Camb)

State Key Laboratory of Pharmaceutical Biotechnology and Collaborative Innovation Center of Chemistry for Life Sciences, Department of Biochemistry, Nanjing University, Nanjing 210093, P. R. China.

Published: April 2017

A simple colorimetric assay is developed for the sensitive and selective detection of an antibody, which combines a protein binding-induced signaling approach with a novel DNAzyme-based conformational switching strategy.

Download full-text PDF

Source
http://dx.doi.org/10.1039/c7cc00687jDOI Listing

Publication Analysis

Top Keywords

detection antibody
8
one-step colorimetric
4
colorimetric detection
4
antibody based
4
based protein-induced
4
protein-induced unfolding
4
unfolding g-quadruplex
4
g-quadruplex switch
4
switch simple
4
simple colorimetric
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!