Fluorescence in a cryptococcoma following administration of 5-aminolevulinic acid hydrochloride (Gliolan).

BMJ Case Rep

Department of Neurosurgery, John Hunter Hospital, New Lambton, New South Wales, Australia.

Published: April 2017

A 54-year-old man presented with two episodes of dysarthria and left facial droop. Both episodes resolved by the time of examination. MRI of the brain revealed a right frontotemporal, heterogeneously enhancing mass with surrounding vasogenic oedema, suggestive of a high-grade primary brain neoplasm. The patient was administered preoperative 5-aminolevulinic acid hydrochloride (Gliolan), and fluorescence-guided resection of the lesion was undertaken. infection was diagnosed from the specimen and the patient was given appropriate antifungal treatment. This is the first reported case of Gliolan-mediated fluorescence in a fungal abscess and highlights one of the potential pitfalls in fluorescence-guided surgery.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534904PMC
http://dx.doi.org/10.1136/bcr-2017-219469DOI Listing

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