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Factors that influence the neurobiological effects of exercise likely extend beyond age and intensity in people with major depression. | LitMetric

AI Article Synopsis

  • A systematic review was conducted on the neurobiological effects of exercise on major depressive disorder, highlighting its benefits.
  • A letter suggested the inclusion of children and adolescents and emphasized the role of exercise intensity in mediating neurobiological responses in depressed individuals.
  • The authors argue that other factors like exercise type, duration, frequency, and adherence also significantly influence neurobiological responses and should be considered in future research.

Article Abstract

We recently conducted a comprehensive systematic review of neurobiological effects of exercise on major depressive disorder. A subsequent letter suggested that we should consider children and adolescent and raised the importance of how intensity may mediate neurobiological response in people with depression. Here, we discuss these comments regarding our review, in addition to proposing that other factors, such type, duration, frequency, and adherence, may also importantly influence neurobiological response, based on recent meta-analyses demonstrating these other aspects of physical activity also moderate dropout rates and effect sizes from exercise upon depression.

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Source
http://dx.doi.org/10.1016/j.neubiorev.2017.04.004DOI Listing

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