Role of the corneal epithelium measurements in keratorefractive surgery.

Curr Opin Ophthalmol

aRio de Janeiro Corneal Tomography and Biomechanics Study Group, Rio de Janeiro bDepartment of Ophthalmology, Federal University of São Paulo, São Paulo cDepartment of Ophthalmology, Pontific Catholic University of Rio de Janeiro, Rio de Janeiro, Brazil dDepartment of Ophthalmology, University of Florida, Gainesville, Florida, USA eDepartment of Ophthalmology, Hospital de Braga, Braga, Portugal.

Published: July 2017

AI Article Synopsis

  • The review highlights the advancements in corneal imaging technology, transitioning from basic topography to complex three-dimensional tomography, enabling detailed analysis of both the front and back surfaces of the cornea.
  • Recent findings emphasize the importance of understanding corneal epithelial thickness and its implications for refractive surgery, including candidate screening and surgical planning.
  • The evolution of imaging techniques, particularly through optical coherence tomography, enhances the safety and effectiveness of refractive and therapeutic eye surgeries.

Article Abstract

Purpose Of Review: Refractive surgery has stimulated considerable progress in corneal and anterior segment imaging, and optical characterization of the eye. From front surface corneal topography, we evolved to three-dimensional corneal tomography with limbus to limbus characterization of the front and back corneal surfaces and pachymetric mapping. Corneal anatomical evaluation has further evolved to layered or segmental tomography with the ability to characterize corneal epithelial thickness profile and the elevation of stromal front surface. Further characterization of even more specific structures, such as Bowman's layer and Descement's membrane, has been also demonstrated. The applications of such understanding in keratorefractive surgery are reviewed.

Recent Findings: Understanding the corneal epithelial profile is of interest in many areas of ophthalmology, especially in refractive surgery. The most relevant applications include screening candidates at higher risk for complications (i.e. progressive ectasia and tear dysfunction syndrome), planning primary procedures, enhancements, and therapeutic surgery, and also postoperatively understanding the wound healing and clinical outcomes.

Summary: Corneal epithelial thickness was first available using digital very-high-frequency ultrasound. Advances in anterior segment optical coherence tomography enabled such fundamental evaluation, which accelerated progress. Such knowledge significantly impacts safety and efficacy of refractive surgery, and also allows for significant improvement for therapeutic procedures. VIDEO ABSTRACT.

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Source
http://dx.doi.org/10.1097/ICU.0000000000000379DOI Listing

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