Objectives: To compare the outcomes of percutaneous image-guided cryoablation of symptomatic abdominal wall endometriosis (AWE) versus surgery alone.
Methods: From 2004 to 2016, cryoablation or surgery alone was performed under local (n = 5) or general anaesthesia (n = 15) for AWE in a single institution in 7 (mean age, 36.1 years) and 13 (mean age, 31.9 years) patients, respectively. Fifteen lesions were treated by cryoablation (mean size, 2.3 cm; range, 0.5-7 cm) and 16 by surgery (2.5 cm; 1.1-3.4 cm). Tolerance, efficacy and patient and procedural characteristics were compared.
Results: Median follow-up was 22.5 (range, 6-42) months after cryoablation and 54 (14-149) after surgery. The median procedure and hospitalisation durations were 41.5 min (24-66) and 0.8 days (0-1) after cryoablation, and 73.5 min (35-160) and 2.8 days (1-12 days) after surgery (both P = 0.01). Three patients (23.1%) had severe complications and nine aesthetic sequels (69.2%) after surgery, none after cryoablation (P = 0.05). The median 12- and 24-month symptom free-survival rates were 100% and 66.7% (95% CI, 5.4; 94.5) after cryoablation and 92% (55.3; 98.9) after surgery at both time points (P = 0.45).
Conclusions: Cryoablation presents similar effectiveness to surgery alone for local control of AWE while reducing hospitalisation duration and complications. Any aesthetic sequels were associated with the cryoablation treatment.
Key Points: • Hospitalisation is shorter after cryoablation than after surgery of abdominal wall endometriosis. • A significantly lower rate of complications is observed after cryoablation compared to surgery. • Cryoablation of abdominal wall endometriosis presents similar effectiveness to surgery alone. • A significant reduction of pain is observed 6 months after treatment. • A significant reduction of abdominal wall endometriosis is observed at 6 months.
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http://dx.doi.org/10.1007/s00330-017-4827-7 | DOI Listing |
Comput Biol Med
January 2025
Department of Mechanical Engineering, Isfahan University of Technology, Isfahan, Iran. Electronic address:
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Department of Urology, University of Health Sciences, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Türkiye.
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January 2025
Department of Emergency Surgery, The Affiliated Hospital of Qingdao University 16 Jiangsu Road Qingdao 266000 P. R. China
The use of mesh repair is a frequently employed technique in the clinical management of abdominal wall defects. However, for intraperitoneal onlay mesh (IPOM), the traditional mesh requires additional fixation methods, and these severely limit its application in the repair of abdominal wall defects. We drew inspiration from the adhesion properties of mussels for the present study, functionalized carboxymethyl cellulose (CMC) with dopamine (DA), and added polyvinyl alcohol (PVA) to the composite to further improve the wet adhesive ability of hydrogels.
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Division of Minimally Invasive and Bariatric Surgery, Penn State Health Milton S. Hershey Medical Center, 500 University Drive, Hershey, PA, 17033, USA.
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