Multidrug Resistant Mycotic Pseudoaneurysm following Cardiac Transplant Bridged by Ventricular Assistant Device.

Case Rep Infect Dis

Infection Management Unit, The Prince Charles Hospital, Brisbane, QLD 4032, Australia; School of Medicine, University of Queensland, Brisbane, QLD, Australia.

Published: March 2017

Mycotic pseudoaneurysm of aorta following cardiac surgery is rare but is highly fatal if it is unrecognized and untreated. Here, we report a case of a 45-year-old male patient who presented with rapidly progressive multiple pseudoaneurysms of the ascending aorta infected with multidrug resistant (MDR) 5 weeks after cardiac transplantation, on a background of prior bridging therapy with left ventricular assistant device (LVAD). The patient was successfully treated with the newer cephalosporin, Ceftolozane/Tazobactam, in combination with surgery. This is the first reported case of mycotic pseudoaneurysm infected with MDR . This case also highlights the importance of high vigilance and timely multimodality treatment in the diagnosis and management of mycotic pseudoaneurysm following cardiac transplant, especially in patients who had LVAD.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366783PMC
http://dx.doi.org/10.1155/2017/1402320DOI Listing

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