Brucella endocarditis is a rare but a severe complication of brucellosis, observed in less than 2% of cases. It is the main cause responsible for up to 80% of deaths in brucellosis. Herein, we present a case of brucella endocarditis that developed on a native aortic valve, but presented to us with fever for several months and acute neurological symptoms. This case report signifies the importance of considering brucella endocarditis as one of the differentials in patients presenting with Pyrexia of Unknown Origin (PUO) and Central Nervous System (CNS) manifestations.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376826PMC
http://dx.doi.org/10.7860/JCDR/2017/22979.9273DOI Listing

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  • Brucellosis is a widespread zoonotic infection that primarily presents as fever but can impact various organs, with endocarditis being the leading cause of death.
  • Proper culture techniques are essential for diagnosing Brucella infections due to the organism's fastidious nature, especially in areas with high prevalence.
  • A case series of three patients with Brucella endocarditis demonstrated successful management through medical therapy and emphasized the need for accurate diagnostics and timely surgical intervention when necessary.
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Introduction: Brucellosis is one of the most common zoonotic infections in the world. Cardiac complications of the disease are usually in the form of endocarditis, and, to a lesser extent, in the form of myopericarditis.

Case: We report the case of a 34-year-old female admitted with signs of fever, nausea, and headache.

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Purpose:  Brucella endocarditis is a rare complication with a high mortality risk. This research aims to evaluate patients diagnosed with Brucella Endocarditis and review clinical characteristics, diagnosis, and treatment strategies to serve as a foundation for future research in managing Brucella endocarditis and improving patient care and outcomes.

Patients And Methods: This retrospective study reviewed the medical records of patients diagnosed with Brucella endocarditis from 2011 to 2022.

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  • * The microbiology of IE has changed, with Staphylococci now being the main culprits, surpassing Streptococci, and new pathogens contributing to more severe cases, which lead to higher morbidity and mortality rates.
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